Because marijuana causes benzodiazepines like Xanax to be metabolized more slowly in the body, it is not recommended to combine the two substances.

Whether it’s an illicit drug, a prescription or an herbal supplement, every consumed substance has possible side effects, interactions and dangers of mixing it with other substances.

What about Xanax and marijuana? These are two substances that are frequently used, and sometimes abused, so what are the possible interactions and dangers of mixing the two? This article will explain.

Interactions and Dangers of Mixing Xanax and Marijuana

Marijuana is known to intensify the central nervous system depressant effects of benzodiazepines like Xanax. Cannabidiol, or CBD, can increase the level of benzodiazepines in your body because it makes it harder for your body to break them down.

This increases the amount of Xanax in your bloodstream. In turn, the side effects of Xanax may be heightened. For example, you may experience severe drowsiness or memory issues. In extreme cases, the risk of a Xanax overdose is possible.If you or someone you know is experiencing extreme side effects, call 9-11 immediately.

Interactions with other substances

Xanax can also have dangerous interactions with other central nervous system depressants like alcohol and opioids. If you mix Xanax with alcohol or opioids, it can lead to slowed breathing and death

Summing Up — Avoid Mixing Xanax and Marijuana

Mixing Xanax and marijuana can increase the amount of Xanax in your body, causing increased Xanax side effects like fatigue and issues with memory.

You may not know how you’ll react to mixing Xanax and marijuana, especially if the marijuana is obtained illicitly and you are not sure how potent it is. People have very different experiences with marijuana.

Always speak to a medical professional before mixing Xanax and marijuana, or any other substances. If you or a loved one develop an addiction, contact The Recovery Village to speak to a representative about how addiction treatment can work for you.

Rob Alston
Editor – Rob Alston
Rob Alston has traveled around Australia, Japan, Europe, and America as a writer and editor for industries including personal wellness and recovery. Read more
Jessica Pyhtila
Medically Reviewed By – Dr. Jessica Pyhtila, PharmD
Dr. Jessica Pyhtila is a Clinical Pharmacy Specialist based in Baltimore, Maryland with practice sites in inpatient palliative care and outpatient primary care at the Department of Veteran Affairs. Read more

U.S. National Library of Medicine. “Xanax,” February 14, 2020. Accessed June 27, 2020.

National Institute on Drug Abuse. “Marijuana Research Report: What is the s[…]n the United States?” April 2020. Accessed June 27, 2020.

National Institute on Drug Abuse. “Marijuana Research Report: What are marijuana’s effects?” April 2020. Accessed June 27, 2020.

Government of the District of Columbia Department of Health. “Medical Cannabis Adverse Effects & Drug Interactions,” Accessed June 27, 2020.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.