Pregabalin is processed quickly by the kidneys and stays in your system for approximately 33 hours, depending on a variety of personal factors. Inform your doctor if you are experiencing any side effects from Lyrica and avoid any interaction medications while it remains in your system.

Lyrica is the brand name for the generic prescription pregabalin. Pregabalin is processed quickly by the kidneys and stays in your system approximately 33 hours, depending on a variety of personal factors. Inform your doctor if you are experiencing any side effects from Lyrica and avoid any interaction medications while it remains in your system.

If you’re unsure about the safety of taking other medications while taking pregabalin or after you’ve stopped taking it, talk to your doctor.

What is the Half-Life of Lyrica (Pregabalin)?

The half-life of a prescription is the approximate time it takes for that medication to reduce to half of its strength after the last dose. Lyrica is well absorbed in the body and is excreted through the kidneys. It has an approximate half-life of six hours.

Factors That Influence How Long Lyrica (Pregabalin) Stays in Your System

There are several factors that influence how long pregabalin will stay in your system. These factors are:

  • kidney function
  • age
  • body mass
  • hydration
  • urinary pH
  • dosage
  • how long you’ve been taking the medication

To determine how long Lyrica might stay in your system after your last dose, consult your doctor. Tell her all your medical history and your habits at home to ensure you get as accurate of a time frame as possible.

How Long Does Lyrica (Pregabalin) Stay in Your Urine, Hair, and Blood?

Lyrica will only be detected in your blood for 2 days after your last dose and will stay in your urine a little bit longer than that. It’s reported that Lyrica can be detected in your urine for a few days depending on your dosage. As with other medications, Lyrica will be detected in your hair for much longer than in your blood or urine, possibly up to 90 days.

Inform your test administrator about any drugs you’re taking and any you’ve stopped taking, including Lyrica, so he can provide you with an accurate test result.

Lyrica (Pregabalin) Prescription Facts

This medication is an anticonvulsant used to treat those suffering from nerve pain due to diabetes or shingles. Although pregabalin doesn’t bind to the GABA neurotransmitters in your brain, it does change the way these neurotransmitters communicate with one another.

Related Topic: What are Anticonvulsants?

Doctors can also prescribe this medication to treat fibromyalgia, prevent seizures, and generalized anxiety disorder.

Pregabalin is taken orally and the dosage depends on what condition is being treated, as well as how your body is responding to it. Most prescription medications come with a chance of side effects. The possible side effects while taking Lyrica are:

  • drowsiness
  • dizziness
  • headache
  • dry mouth
  • nausea
  • constipation
  • weight gain

Some more serious side effects can occur with pregabalin; such as, vision changes, unusual bleeding/bruising, muscle pain/tenderness/weakness, fever, and swelling of your hands, ankles, or feet.

As with other anticonvulsants, there is a small chance of mental changes, causing thoughts of suicide or signs of depression. If you experience any side effects, either physical or mental, talk to your doctor. She will help you decide if Lyrica is the right medication to treat you.

Related Topic: First Aid for Suicidal Thoughts and Behaviors

Feelings of depression or anxiety can lead to suicidal thinking. If you or a loved one is experiencing suicidal thoughts or tendencies, call the National Suicide Prevention Hotline at 1-800-273-8255.

Do not stop taking pregabalin abruptly without the help of a medical professional because you may experience withdrawal symptoms. These may include headaches, upset stomach or nausea, diarrhea, trouble sleeping, increased sweating, and anxiety.

Lyrica (Pregabalin) Regulations

Lyrica is listed as a Schedule V controlled substance under the Controlled Substance Act (CSA). This means that pregabalin is a drug that may be distributed or dispensed only for medical purpose. Pregabalin can only be legally prescribed by a qualified doctor who has determined this medication to be the best to treat your condition.

Most Commonly Abused Drugs Containing Lyrica (Pregabalin)

Due to the opioid crisis, many people are turning to anticonvulsants as a means of relieving pain. As a result, it’s been recently reported that many are misusing the prescriptions for the euphoric effect.

If you feel you or a loved one is misusing pregabalin, don’t wait to get help. Call 24/7 to our toll-free hotline at 855-504-4942 to learn more about the road to recovery. We can help you overcome your addiction today.

How Lyrica (Pregabalin) Affects the Brain and Body

Lyrica changes the way the GABA neurotransmitter communicates in your brain, affecting your nervous system and treating your condition. While taking Lyrica, there is a chance of side effects affecting your body and your brain, so report any unexpected changes in your body or mind to your doctor right away.

Taking pregabalin can cause your body to become dependent on it. If you suspect that this is happening to your body, seek help from a trusted medical professional.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.