Mixing alcohol and Bactrim is not entirely safe.
Article at a Glance:
There are several important points to remember about alcohol and Bactrim use.
- Overall, it is not recommended to drink alcohol while taking antibiotics
- The combination of Bactrim and alcohol specifically can cause serious side effects
- If you require antibiotics and plan on drinking alcohol, be sure to tell your doctor
- If you are finishing up a course of Bactrim, wait about a week before drinking alcohol
Alcohol and Bactrim
Mixing alcohol and Bactrim is not entirely safe. Alcohol can interact with many types of medication, including antibiotics like Bactrim. A general rule to follow is that if you are sick enough to require antibiotics, you should not be drinking alcohol. However, alcohol is a common part of social lives. Whether it’s a wedding, date, or birthday party, you may be interested in having a drink while on an antibiotic.
Bactrim is a commonly prescribed antibiotic used to treat bacterial infections including those in the ear, urinary tract, and respiratory system. You may know it by its generic name, sulfamethoxazole-trimethoprim, or SMZ-TMP.
While some antibiotics may be taken with moderate alcohol consumption, Bactrim is not one of them. Potentially harmful side effects can occur if you mix alcohol and Bactrim.
Side Effects of Mixing Alcohol and Bactrim
Your body relies on specific enzymes to break down alcohol into something that can be easily eliminated. Through this complex process, several byproducts are created. One of the byproducts is a toxic substance called acetaldehyde.
Bactrim may prevent the enzyme responsible for breaking down acetaldehyde from working, creating a buildup of the toxic substance. This interaction can lead to many side effects, including:
- Flushing
- Headaches
- Nausea and vomiting
- Difficulty breathing
- Headache
- Rapid heart rate
These effects may occur five to 15 minutes after consuming alcohol.
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Steckelberg, James M. “What are the effects of drinking alcohol[…] taking antibiotics?” The Mayo Clinic, 2018. Accessed March 22, 2019.
Heelon, MW, White, M. “Disulfuram-cotrimoxazole reaction.” Pharmacotherapy, 1998. Accessed March 22, 2019
Drugs.com. “How long does it take Bactrim DS tabl[…]t of your system?” Updated July 2018. Access March 2019.
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