When you’re taking a prescription drug, it’s important that you’re aware of all potential interactions, side effects, and reactions. It can be easy to think that if you mix an over-the-counter drug with a prescription medicine that it’s safe, but this is often not the case.

That’s why it’s so important to let your physician know if you’re taking anything else including not only other prescriptions but also over-the-counter medicines, supplements, and vitamins.

Two commonly used substances are Xanax and Advil, but can you take them together?
The following provides more information about Xanax and Advil separately from one another, and also answers “can you take them together?”

Xanax and Advil | Can You Take Them Together?
Before looking at possible interactions between Xanax and Advil, what is Xanax?

Xanax is a very commonly prescribed anti-anxiety medicine that’s classified as a benzodiazepine. The generic name is alprazolam, and it helps to balance certain chemicals in the brain that contribute to anxiety, as well as panic disorders.

There is a pretty high potential of Xanax becoming habit-forming, and people are warned about this when they start taking it. When someone abuses Xanax, it can also lead to not only addiction but an overdose or death. People are warned against combining Xanax with substances like alcohol as well because it can further increase these risks.

Some of the possible adverse side effects of Xanax may include depression, confusion, or hallucinations. These are more severe but less common side effects, while more common side effects of Xanax may include feeling drowsy, slurred speech, lack of coordination and balance, or memory problems.

There are quite a few drugs that may interact with Xanax including narcotic pain medicines and muscle relaxants. The reason these should be avoided is because they can slow the respiratory system to the point where you stop breathing or die.

Before answering “can you take them together,” about Xanax and Advil, what is Advil?

Advil is a common over-the-counter pain reliever with the generic active ingredient ibuprofen. It can also be used to treat fevers, and it reduces inflammation. Ibuprofen is classified as a nonsteroidal anti-inflammatory drug or an NSAID that can help with mild to moderate pain.

Advil is considered relatively safe, but it can lead to severe side effects in rare situations such as bleeding of the stomach or intestines. This is especially risky in people who have had a stomach ulcer, or who regularly drink.

So what about Xanax and Advil? Can you take them together, or are there possible interactions?

There are a few things to know about the relationship between Xanax and Advil. First, with regular Advil, there are really no known interactions that would make it risky to take them together, at least not based on what’s known currently.

However, if you use Xanax and Advil PM together, it could lead to side effects.

Advil PM is a brand name product which is a combination of ibuprofen and something called diphenhydramine. It can be used to treat symptoms from a variety of conditions such as minor aches and pains, or pain from the flu or colds.

This combination medicine also contains diphenhydramine, which is an antihistamine that can relieve certain cold or flu symptoms like a runny nose but also causes drowsiness. Many of the general warnings that come with the use of Advil PM are similar to warnings for regular Advil and include the risk of stomach bleeding or ulcers in particular.

People are also warned against mixing alcohol and Advil PM, but the makers say it isn’t habit-forming like other sleep aids might be.

Even though Advil PM is considered relatively safe on its own, it shouldn’t be mixed with Xanax. The reason you shouldn’t mix Xanax and Advil PM is because it can increase certain side effects including drowsiness, dizziness, confusion and concentration problems.

There is also the risk that if you mix Xanax and Advil, it can cause impaired coordination, thinking, and judgment. You should avoid anything involving mental alertness if you take Xanax and Advil together, and the risks are even higher in elderly people.

It should also be noted that while there aren’t specific warnings about the interaction between Xanax and Advil in its regular form, you should always speak to your doctor about combining medicines, or anything else you’re taking before you start taking something like Xanax. Ultimately it’s only your doctor who can answer “can you take them together” when it comes to Xanax and Advil, or any other medicines that you may be taking simultaneously.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.

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