Though people who receive depression treatment may experience a significant reduction of their symptoms, a depression relapse is still possible over time. In fact, research shows that almost half of people who discontinue treatment for depression will relapse within a few months. While depression relapse statistics show that this condition is likely, there are steps people can take to prevent depression from returning.

What Is Depression Relapse?

Most depression relapse definitions are similar, and each provides additional information about what this type of relapse looks like. According to medical professionals, relapse occurs when a person returns to meeting the full diagnostic criteria for depression after being in remission. In other words, a depression relapse is when someone becomes depressed again after feeling better for a period of time.

Signs of a Depression Relapse

Since a relapse means a return to depression, depression relapse symptoms are the same as those associated with major depressive disorder. A person who has relapsed into depression may also have thoughts of suicide or feel hopeless or worthless.

  • Common signs of a depression relapse:

    • A lack of interest in previously enjoyable activities
    • Sleeping more or less than usual
    • Eating more or less than usual
    • Changes in weight
    • A persistent mood of unhappiness
    • Low energy levels
    • Moving more slowly than normal
    • Feeling physically uncomfortable without any medical reason
    • Irritability or anxiety

Common Relapse Triggers

Certain depression relapse triggers can increase a person’s risk of returning to depression. These can include any of the following:

  • Stressful life events:

    Stress and depression can go hand in hand, and coping with life’s stressors can cause a person to slip back into depression. One study found that women with a history of depression were more likely to relapse after experiencing negative life events or stressors like financial difficulties.

  • Family history of depression:

    When depression runs in the family, a person may be more likely to relapse. Research shows that when a parent has depression, children are significantly more likely to experience recurring depression.

  • Discontinuing treatment:

    Depression relapse after stopping medication appears to be common. An analysis of multiple studies shows that the relapse rate is about double for people who stop treatment compared to those who continue to take medication treatment for depression.

  • Other medical conditions:

    Having another health condition can increase the risk of depression relapse. One study found that depression relapse was common among people diagnosed with diabetes. Depression relapse is also more common among people with conditions like anxiety and substance use disorders.

Preventing Depression Relapse

A depression relapse prevention plan can help reduce the risk of recurrence. A person may develop a plan with a counselor before ending regular treatment sessions, and it can include a list of relapse triggers, signs of relapse and tools for coping with stressors. Being able to recognize signs of an impending relapse can help a person prevent a full relapse from occurring.

A relapse prevention plan may include beneficial activities, such as regular exercise, meditation or spending time with friends. It may also include a list of steps to take if signs of relapse appear.

The Importance of Maintenance Treatment

A depression relapse prevention plan should also include maintenance treatment. This might include monthly check-ins with a therapist. Medication is also an important component of maintenance treatment. Because most antidepressants are effective for preventing depression relapse, continuing to take medication under the supervision of a doctor can be important for long-term recovery from depression.

Treating a Depression Relapse

For people experiencing the return of depression symptoms, it is important to know how to cope with depression relapse. Various therapies and treatments are effective for treating depression.