Remifentanil How Long Does It Stay in Your System?

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Remifentanil is an opioid agonist administered through injection in a hospital setting to relieve pain. Pain relief from Remifentanil is very fast and often begins in as little as 60 seconds. Remifentanil will stay in your system for about 2 hours after your last dose. The exact time frame Remifentanil stays in your system varies depending on several factors outlined below.

Inform your caregivers if you are experiencing any side effects from Remifentanil and avoid taking any interactive medications while it remains in your system. You should take care to especially avoid alcohol or any other central nervous system depressant drugs.

If you’re unsure about the safety of taking other medications or consuming alcohol while receiving Remifentanil, or after being treated with this prescription drug, talk to your doctor.

Remifentanil How Long Does It Stay in Your System?
Remifentanil is a powerful short-acting synthetic opioid pain reliever. It’s given intravenously during and after surgery to not only relieve pain, but also as an anesthetic. Remifentanil should be given through an infusion pump to ensure proper dosage.

Some common side effects from Remifentanil are itching, sweating, headache, muscle pain, cough, sore throat, dizziness, confusion, and agitation.

Remifentanil can cause other, less common, side effects, including:

  • Weak, shallow breathing
  • Breathing that stops
  • Fast or slow heart rate
  • Stiff muscles
  • Severe weakness, feeling light-headed or fainting.

If you experience any of the aforementioned side effects or notice any changes after receiving a dose of Remifentanil, inform your doctor right away. Some side effects can turn out to be serious and it is better to be cautious.

Remifentanil is present in Ultiva and is highly addictive. Although Remifentanil is administered in a hospital setting, it has been obtained and misused without a prescription and without direction from a doctor. Doing so is dangerous.

Your doctors are the only ones who should administer Remifentanil, and this should be while in the hospital under strict care. Do not inject Remifentanil on your own, doing so could lead to respiratory depression and death.

Remifentanil affects your central nervous system to change the way your body feels pain. In doing so, it also depresses your respiratory system and has a chance of causing hypotension in your heart. Remifentanil is an opioid agonist, which means the medication binds with opioid receptors to produce the desired biological response, pain-relief and sedation.

This prescription also affects the gastrointestinal and immune systems.

If you have been taking Remifentanil without a doctor or outside of a hospital setting, do not abruptly stop taking the opioid. Seek help. As mentioned above, go online to or call 24/7 to our toll-free hotline at 855-548-9825 to learn more about the road to recovery.

The half-life of a medication is the time it takes for the effectiveness to be cut in half after a person takes his or her last dose. The terminal half-life for Remifentanil is about 20 minutes.
There are several factors that influence how long Remifentanil will stay in your system after the last dose. These factors include age, sex, other medications, liver function, kidney function, and dosage.

Your doctor can help to determine the approximate time frame Remifentanil will stay in your system, based on your unique factors. Inform your doctor of your complete medical history to ensure the highest level of care.

Remifentanil is an opioid and will show up in a drug test screening, so you need to inform the drug test administrator that you are taking or have recently taken this prescription. Remifentanil is fast-acting and administered only at the hospital, so it’s unlikely you will have a drug test in the time it will be in your system.

Remifentanil will be detectible in your urine and blood for about 2 hours, but it remains in your hair considerably longer. Drug tests on your hair can show traces of most prescription drugs for up to 90 days after the last administration.

If you or a loved one is suffering from a substance use disorder, it’s never too late to recover. Go online to or call 24/7 to our toll-free hotline at 855-548-9825 to learn more about living a drug-free life. We can help you overcome your addiction today.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.