Palladone Addiction and Abuse

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Palladone is an extended-release capsule version of the analgesic opioid hydromorphone hydrochloride. It’s a potent painkiller that provides constant pain relief for the management of severe chronic pain. Palladone is derived from morphine and is approximately five times stronger.

Common side effects of Palladone include nausea, vomiting, constipation, dizziness, dry mouth, weakness, nervousness, drowsiness, itching, and headache. Constipation is the most frequently occurring side effect and is common for all opiates. Palladone reduces the motility of the smooth muscles in the small intestine. Constipation rarely goes away without the use of stool softeners and laxatives.

Several conditions can affect the metabolization of Palladone in the body and increase the risk of complications. Talk to your doctor if you have a history of liver or kidney problems, breathing issues like asthma, wheezing, low blood pressure, gallbladder problems, hypothyroidism, or difficulty urinating.

Palladone Addiction and Abuse

Palladone is most commonly prescribed for the management of chronic pain. It’s available in 12 mg, 16 mg, 24 mg, and 32 mg extended-release capsules. Palladone is an opioid agonist. It achieves its effects by binding to specific opioid receptor sites that modulate the body’s pain response.

Palladone produces major depressant effects on the central nervous system and the gastrointestinal tract. One of the primary effects of Palladone and other opioids is the depression of respiratory drive. In the case of an overdose, severe respiratory depression can lead to coma and death.

Palladone is a highly addictive opioid. In 2015, 33,000 deaths occurred in the United States as a result of opioid overdose. Of these, 15,000 were due to prescription medications. Physicians are advised to only administer Palladone in cases in which other, less-addictive medications have proved to be inadequate. Palladone is administered for the treatment of chronic pain, especially in individuals who already have a high tolerance for synthetic and semi-synthetic opioids.

Patients must be monitored closely for developing physical dependence. Regular opioid use can result in components of physical, psychological, and behavioral addiction. Individuals may become fixated on obtaining more of the drug while neglecting other responsibilities in their personal and professional life. Taking too much Palladone can cause blood pressure to dramatically drop. This may lead to dizziness and the inability to stand from a seated position. Notify your doctor immediately if you experience such symptoms.

Patients should be closely monitored for respiratory depression when first beginning Palladone treatment. A common cause of hospital overdose cases is inadequate patient care during initial treatments with powerful opioids. Patients should never mix other opioids or central nervous system depressants without doctor approval due to the risk of severe respiratory depression and death. Other substances that should not be mixed with Palladone include benzodiazepines, barbiturates, MAO inhibitors, anti-anxiety medications, and alcohol. Alcohol can interfere with the liver’s ability to process Palladone and lead to elevated blood plasma levels of the drug.

Individuals that want to stop taking Palladone should discuss this with their doctor before discontinuing use of the drug. Stopping treatment abruptly can trigger the onset of severe withdrawal symptoms. The prescribing physician will likely recommend opioid replacement therapy for people who have used the drug for a long time. Replacement therapy involves supplementing Palladone with other longer-acting, less powerful opioids to gradually wean the patient off the drug.

If you or someone you know is struggling with opiate abuse or discontinuing opiate use, The Recovery Village is here to help. Call our toll-free hotline at 855-548-9825 or visit us online at