How Long Does Nucynta Stay in Your System?
- 1. How Long Does Nucynta Stay in Your System?
- 2. Nucynta Prescription Facts
- 3. Nucynta Regulations
- 4. Most Commonly Abused Drugs Containing Nucynta
- 5. How Nucynta Affects the Brain and Body
- 6. Half-Life of Nucynta
- 7. Factors That Influence How Long Nucynta Stays In Your System
- 8. How Long Does Nucynta Stay In Your Urine, Hair, and Blood?
Nucynta can remain at testable levels in the urine for up to three to four days following the time of last dose. Nucynta has a half-life of roughly four hours. This is the amount of time it takes for half of the drug’s contents to be eliminated from the body. More than 95% of Nucynta is excreted within the first 24 hours.
Nucynta should not be taken concurrently with muscle relaxants, tranquilizers, anxiolytics, benzodiazepines, non-benzodiazepine sedative/hypnotics, antipsychotics, or general anesthetics. The combination of Nucynta and alcohol can result in the conflicting enzymes in the liver. This can lead to extended clearance rates and elevated concentrations of Nucynta in the blood plasma. Extended clearance times and elevated plasma concentrations greatly increase the risk of opioid toxicity and overdose.
Nucynta should also not be combined with serotonergic drugs like selective serotonin reuptake inhibitors (SSRIs), tricyclics, or MAO inhibitors uses to treat depression. The concomitant consumption of Nucynta with the substances can lead to a potentially fatal condition of serotonin overload. Serotonin syndrome can cause irreversible psychosis.
Nucynta achieves its pain-relieving effects by binding to specific opioid receptors. Nucynta does not rely on the body metabolizing it to achieve its therapeutic effects. This makes Nucynta especially useful in treating pain in patients who are genetically predisposed to poorly metabolizing other opioids. Most opioids rely heavily on the liver to process the drug into metabolites which can then be used by the body. Nucynta can bypass this mechanism.
Common side effects of Nucynta include drowsiness, dizziness, nausea, vomiting, dry mouth, fatigue, sleepiness, itchiness, and headache.
Elderly patients tend to require lower doses due to suboptimal functioning of the liver and kidneys which are responsible for processing the drug. Certain individuals are genetically predisposed to longer elimination times due to a lack of the enzymes required to metabolize Nucynta. Enzymatic complications are less common with Nucynta when compared with other synthetic opioids.
If you or someone you love is struggling with opioid misuse, The Recovery Village is available to answer any questions you may have.
Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.
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