Lortab Strengths: Dosage Guide

Lortab was previously a controlled substance. This is because it contained the opioid hydrocodone. Opioids like hydrocodone have a high likelihood of abuse and dependence, even when they’re taken as directed by a doctor, so it’s incredibly important to understand dosages and varying Lortab strengths before you take this Schedule II medicine. Lortab is no longer available on the market in pill or tablet form. It is still available as a liquid.

This prescription medicine contained not only hydrocodone but also acetaminophen. Acetaminophen is found in brand-name Tylenol, and while it’s not habit-forming, it also has its own set of risks. Acetaminophen treats pain differently from hydrocodone, but it can still cause liver damage or even liver failure if too much is taken in a certain window of time. The acetaminophen component is just one more reason Lortab strengths and doses are relevant to people taking this medicine.

Lortab Strengths: Dosage Guide
Lortab used to come in several different strengths, starting with 2.5/325 mg. The first number refers to how much hydrocodone is in the dose, and the second refers to the acetaminophen. When you take Lortab 2.5/325 mg, some of the side effects are similar to any narcotic pain reliever and can include nausea, vomiting, drowsiness, changes in mood, headache, anxiety, blurred vision or dry mouth. Among those side effects, some of the most common with this Lortab strength are drowsiness, nausea, vomiting and constipation.

With Lortab 2.5/325 mg, patients were usually advised to take one to two tablets every four to six hours as needed for pain.

The next strength of Lortab that used to be commonly prescribed was 5/325 mg. This dosage of Lortab was also taken on an as-needed basis for pain every four to six hours, but patients were advised only to take one tablet at a time, but in some cases of severe pain, two tablets were necessary. The maximum total daily dosage of 5/325 mg Lortab is 12 tablets, as this keeps daily acetaminophen consumption under 4000 mg.

The two highest Lortab strengths were 7.5/325 mg and 10/325 mg. With these Lortab strengths, patients were usually told to take one tablet every four to six hours for pain, and not to exceed six tablets in a day. Varieties in 5/300 mg, 7.5/300 mg and 10/300 mg doses were also available.

Again, it’s important to realize that acetaminophen was in Lortab of all strengths, and it has been associated with acute liver failure. If acute liver failure occurs, it can necessitate a liver transplant or it can lead to death. Most instances of acetaminophen-linked liver damage are when people take more than 4000 mg in a day. It’s important to keep in mind that many prescriptions and other over-the-counter pain and cold medications also contain acetaminophen and to take this dosage into account when calculating the amount of acetaminophen consumed in a day.   

Regardless of which of the Lortab strengths taken, the following are some general side effects of this prescription pain medication:

  • Opioids have an impact on the central nervous system. While this effect helps relieve pain, it can also contribute to feelings of confusion or mental cloudiness, coordination problems and lethargy.
  • Physical dependence is a major side effect of prescription opioids like Lortab. Physical dependence occurs when a person builds a tolerance to a drug and their body becomes used to its presence. Then, when they stop taking it, they experience withdrawal symptoms.
  • Opioids frequently cause gastrointestinal side effects, the most common of which is constipation. Urine retention may also occur.
  • Hydrocodone, as with other opioids, depresses the respiratory system because of its impact on the central nervous system. This can lead to slowed breathing or more serious problems, particularly with higher Lortab strengths and doses.

To sum up, there were previously a few Lortab strengths available, with the hydrocodone component starting at 2.5 mg and going up to 10 mg. These numbers are based on the hydrocodone in Lortab, and the acetaminophen strength most commonly prescribed is 325 mg.

Lortab Strengths: Dosage Guide
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