Synthetic heroin is a blanket term used for all heroin that is manufactured in labs. Some synthetic heroins are very potent and can be more deadly than heroin.

Heroin is a drug that’s front and center in the opioid epidemic taking place in the U.S. right now. Heroin is powerful, inexpensive and relatively easy to obtain, and is used by many people who are addicted to opioids.

Also relevant to the heroin and opioid epidemic in the U.S. is synthetic heroin. Below is an overview of what synthetic heroin is and how to identify it.

Synthetic Heroin

Opioids are drugs that have long been used for medicinal and recreational purposes. Opioids include both natural opiates derived from the poppy plant, such as opium and morphine, and man-made opioids that are synthetic drugs made from morphine. Opioids are available by prescription in the U.S. and are used to treat pain. Most prescription opioids are considered synthetic, and this means that while they act like natural opioids that come directly from the poppy plant, they are man-made.

There are only a few natural opiates that are used in medical settings, including morphine. Opium (a naturally occurring opiate) was used for medical reasons at one point but it is no longer used in clinical settings. Morphine and codeine are controlled substances in the U.S., which means only a qualified medical professional can prescribe them for pain relief.

Codeine is typically more commonly abused than morphine because it’s easier to get and it’s available as a prescription cough syrup. Other opioid drugs include methadonefentanyloxycodonehydrocodone, and heroin.

Heroin is one of the most widely abused of all opioid drugs. It’s made from morphine and then synthesized. Once someone takes heroin, it converts back into morphine in their brain before binding to the opioid receptors.

As cases of opioid addiction have become more prevalent over the years, there has been a rise in something called synthetic heroin. Synthetic heroin is an umbrella term which most often refers to drugs like Dilaudid or hydromorphone. Fentanyl is another drug that is commonly referred to as synthetic heroin. Fentanyl is incredibly powerful and often causes people to overdose after taking it. Fentanyl is so powerful that it can be dangerous to people who touch it or accidentally inhale it.

What is Synthetic Heroin?

It can be difficult to define exactly what synthetic heroin is because this is a blanket term that can be used to refer to different substances. One example of synthetic heroin is fentanyl, and another is carfentanil.

Fentanyl is an opioid pain medication that is considered to be 50 times more potent than heroin, but in many ways mimics the effects of morphine. Fentanyl was first introduced as a pain reliever for palliative care, but it’s since become one of the most widely used synthetic opioids. People may knowingly take fentanyl because of the powerful and rapid effects it can deliver, but they may also accidentally take it.

For example, so-called synthetic heroin is often mixed with heroin or is sold as a different medicine than what it really is. It’s led to many overdose deaths in recent years. Combining even just a small percent of fentanyl with heroin greatly decreases the amount of oxygen to the brain, which contributes to fentanyl overdose deaths.

Carfentanil is also often called synthetic heroin, and this is a derivative of fentanyl. Carfentanil is 100 times more powerful than fentanyl, meaning it’s 10,000 times more potent than morphine. It’s used to sedate large animals like elephants, and it doesn’t have approved human uses. It’s incredibly powerful and when veterinarians use it, they have to wear protective clothing.

Even in people with a tolerance for opioids, an amount of carfentanil the size of a salt grain can lead to overdose and death.

Synthetic Heroin Name

As mentioned, the term synthetic heroin refers to several different substances, and the synthetic heroin name is loosely given to a variety of substances.

For example, the synthetic heroin name might just be used to refer to prescription opioids that act on the central nervous system in a way that’s similar to heroin, or it can be used to refer to incredibly powerful and completely synthetic substances like fentanyl and carfentanil. Because synthetic heroin leads to depression of the central nervous system and respiratory system, the use of this drug can cause breathing to stop.

In some cases, the synthetic heroin name may even be used to refer to methadone, which acts somewhat like an opioid but is designed to help people stop using heroin and other opioids.

There is also something called China White that’s relevant to the discussion of synthetic heroin. China White is a name that refers to derivatives of fentanyl. It’s similar to heroin and morphine but much more potent, and the overdoses that occur with China White are very difficult to treat. China White often contains a variety of substances including fentanyl as well as heroin and cocaine in many cases.

What Does Synthetic Heroin Look Like?

It’s difficult to answer, “What does synthetic heroin look like?” because it comes in so many forms and versions. For example, someone might think they’re buying a pure powder form of heroin, but it could be laced with fentanyl. Someone might also think they’re buying a prescription painkiller, but it could be a different drug.

Synthetic heroin can look very much like conventional heroin, which is what makes it so dangerous and often deadly.

Synthetic heroin tightly binds to the brain’s opioid receptors. If someone overdoses on synthetic heroin, several doses of Narcan (naloxone) may be needed to reverse the drug’s effects.

a woman in a black cardigan smiles at the camera.
Editor – Camille Renzoni
Cami Renzoni is a creative writer and editor for The Recovery Village. As an advocate for behavioral health, Cami is certified in mental health first aid and encourages people who face substance use disorders to ask for the help they deserve. Read more
a woman taking a selfie with her cell phone.
Medically Reviewed By – Frances Antoinette Aguilar, PharmD
With over 11 years experience in academic, hospital, and ambulatory pharmacy, Frances has a demonstrated history of working in the hospital and healthcare industry, assisting physicians with the development of pathways or protocols to improve clinical practice. Read more

Armenian A, Vo KT, Barr J, Lynch, K. “Fentanyl, fentanyl analogs and novel […]rehensive review.” Neuropharmacology, 2018. Accessed January 2019.

Butterfield, Michelle. “P.E.I. Police Photo Shows Just How Li[…]It Takes To Kill.” Huffington Post, 2017. Accessed February 2019.

Centers for Disease Control and Prevention. “Synthetic Opioid Overdose Data.” Last updated December 18, 2018. Accessed February 14, 2019.

Koyyalagunta, Dhanalakshmi. “Chapter 113 – Opioid Analgesics.” Pain Management. Volume 2. 2007. 939-964.

Mars SG., Bourgois P, Karandinos G, Montero F, Ciccarone, Daniel. “Research paper: “Every ‘Never’ […]heroin injecting”. International Journal of Drug Policy. March 2014 25(2):257-266.

Volkow, F. Collins. “The role of science in addressing the opioid crisis.”  NEJM, 377 (2017), pp. 391-394.

PubChem. “Carfentanil.” (n.d.) Accessed February 14, 2019.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.