Article at a Glance:

  • Pristiq is an antidepressant medication that works by increasing the absorption of norepinephrine and serotonin in the brain.
  • Pristiq is very powerful and can result in addiction.
  • Withdrawal symptoms of insomnia, anxiety, night terrors, and tingling can result after stopping Pristiq.
  • Pristiq should never be taken with alcohol, illicit drugs, blood thinners, or NSAIDs.

Signs, Symptoms and Side Effects of Pristiq (Desvenlafaxine)

Pristiq is part of the new generation of antidepressant medications. Pristiq works by increasing the absorption of serotonin and norepinephrine in the brain. This increased absorption can help to elevate mood levels and decrease symptoms of anxiety and depression.

Pristiq is a very powerful drug and can bring on the psychological disease of addiction. Pristiq addiction can be difficult to diagnose because the symptoms can match the possible side effects of this drug. Some of the most common side effects of desvenlafaxine include: excess sweating, dizziness, agitation, drowsiness, constipation, loss of appetite, dry mouth, nausea, weight loss, blurred vision, and decreased sex drive.

These unpleasant side effects often go hand in hand with addiction, so how can you know if you’re experiencing the regular side effects of Pristiq or have started suffering from a psychological disease? If the symptoms become severe, or you want to stop taking Pristiq but don’t know how, consult a medical professional.

It is normal for the body to become accustomed to prescription medication and it is best to monitor your Pristiq symptoms with the help of a professional. If at any time you experience these less common, but more dangerous symptoms during Pristiq use, seek medical help right away: difficulty urinating, stiff muscles, hives, uncontrollable impulses, blurred vision, sudden aggression, falling down, increased depression, and/or suicidal thoughts.

What Is Pristiq (Desvenlafaxine)?

Desvenlafaxine is the generic name for the antidepressant medication marketed as Pristiq. Pristiq is used to help stabilize moods and the substance is classified as a serotonin–norepinephrine reuptake inhibitors (SNRIs). Most often, it is prescribed to those experiencing major depressive disorder. Pristiq may also be prescribed to treat anxiety, obsessive-compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), and fibromyalgia.

The symptoms of mood disorders occur because of an imbalance of the neurotransmitters in the brain. Desvenlafaxine works as an SNRIs by regulating the neurotransmitters in the user’s brain. Once regulation occurs, the person taking the drug may feel happy, relaxed, and develop an increased ability to focus and sleep.

Pristiq is considered up to ten times more effective at regulating these neurotransmitters than its antidepressant predecessors. It is also popular because it has less severe side effects than many comparable antidepressants. This makes it popular for doctors to prescribe to patients who may have had a bad experience with another antidepressant previously.

Due to its popularity and effectiveness, Pristiq is one of the most common antidepressants.

Pristiq (Desvenlafaxine) Dependence

Physical dependence happens when the patient feels wholly reliant on taking the drug to feel ‘normal.’ If you stop taking desvenlafaxine and experience withdrawal symptoms, it is likely you could be experiencing this with Pristiq. The symptoms that occur as Pristiq is cleansed from your body include headaches, anxiety, mood swings, nausea or vomiting, insomnia, fatigue, dizziness, night terrors, and tingling or shock sensations.

If you’ve tried to stop taking Pristiq and experienced these uncomfortable symptoms, consult a medical provider to ensure proper precautions are being taken to protect your mental and physical health. In most cases, withdrawal symptoms will decrease if you slowly decrease your dosage of desvenlafaxine over time. Stopping Pristiq all at once could cause a surge of unpleasant and possibly dangerous symptoms.

It is important to keep in mind that Pristiq should not be combined with alcohol or other other drugs. Pristiq can interact with other mind-altering substances and cause unwanted symptoms in the body. If you are trying to stop taking Pristiq, it is necessary to avoid recurrence of use throughout the tapering off process.

Pristiq (Desvenlafaxine) Long-Term Effects

As with all antidepressants, they may take 4-8 weeks for you to see the full benefits of the medication. As soon as you start taking Pristiq, it’s important to monitor your overall mood, appetite, and side effects so that your doctor can get you on the correct dosage for maximum effectiveness. If taking this medication as directed and properly dosed, the long-term effects should be minimal. To avoid unwanted effects, do not start, stop, or change your dose without medical guidance.

When considering the long-term effects of desvenlafaxine, it is important to keep in mind possible drug interactions. If you’re taking Pristiq alongside certain drugs or alcohol, the long-term effects could be harmful or in some cases, lethal. Pristiq should absolutely not be combined with alcohol. Pristiq should also never be taken with illicit drugs, NSAIDs (like ibuprofen), blood thinners, or drugs that can cause bruising and bleeding.

If you or someone you know is experiencing unwanted side effects from Pristiq (desvenlafaxine), seek medical help to ensure proper stoppage or dosage of the prescription drug. The Recovery Village has highly trained support available to help people battling substance use disorder to live a drug-free life.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.