Understand what to expect during Percocet withdrawal & detox – physical and psychological withdrawal symptoms, how long detox takes, tapering, and dealing with relapse.

Article at a Glance:

  • Abruptly stopping the use of opioids is not recommended.
  • Physical dependence is not uncommon and can result in a withdrawal syndrome when Percocet use is discontinued.
  • Your experience with Percocet withdrawal will vary depending on how long you’ve been using Percocet, as well as the dosage.
  • Physical and psychological symptoms may occur as soon as four hours after you take your last dose. Pain, including pain in your muscles, back, and joints and sleep disturbance are also common.

An Overview

If you use Percocet long enough, your body will eventually become dependent on the drug. When this happens, if you try to stop using it, you’ll likely experience some physical and psychological withdrawal symptoms. The first days of Percocet detox are usually the hardest.

To have the best chances for success, medical supervision and the assistance of trained professionals is essential. In a medical detox program, opioid use is gradually tapered off to avoid withdrawal symptoms, prescription detox medications are used to help ease symptoms of withdrawal, and individual and group counsel can assist with the psychological symptoms you may experience.

Percocet Withdrawal Symptoms

Abruptly stopping the use of opioids is not recommended. Physical dependence is not uncommon and can result in a withdrawal syndrome when use is discontinued. Symptoms may include restlessness, excessive tearing, runny nose, yawning, sweating, chills, muscle pain, upset stomach, nausea, vomiting, and diarrhea. Psychological symptoms may include feelings of irritability, and anxiety.

Pain is also common, including pain in your muscles, bones, and jointsSleep disturbance is also common. Keep an eye on increased blood pressure, respiratory rate or heart rate, as these could be serious signs that something is wrong.

Physical Symptoms of Percocet Withdrawal

Some physical symptoms of opioid withdrawal are:

  • Nausea
  • Vomiting
  • Sweating
  • Runny nose
  • Tearing
  • Diarrhea
  • Cramps
  • Muscle spasms and aches
  • Fatigue
  • Tremors
  • Hot or cold spells
  • Insomnia
  • High blood pressure
  • Dilated pupils

Psychological Symptoms of Percocet Withdrawal

Some psychological symptoms of Percocet withdrawal include:

  • Irritability
  • Anxiety
  • Agitation / Aggression
  • Depression
  • Mood swings
  • Inability to concentrate
  • Paranoia
  • Hyperactivity

Percocet Withdrawal Timeline

Percocet withdrawal symptoms can begin as soon as four hours after you take your last dose of the narcotic. If you have been taking Percocet for a long period of time, these symptoms may take longer to manifest. For most people, Percocet withdrawal will last at least one week. Chronic users may experience withdrawal for up to three or four weeks.

The severity of your withdrawal symptoms, how quickly they begin and how long it takes to stop experiencing withdrawal will vary depending on several factors:

  • How long you abused Percocet
  • How much of the narcotic you were taking
  • How you consumed the drug
  • If you are abusing more than one drug at a time

The following timeline will provide you with a general idea of what the detox process will look like.

  • Days 1-3: Percocet has a half-life of 4 hours for a single dose, so symptoms of withdrawal will likely peak in severity and intensity on the first day. For many, the physical feelings of pain, accompanied by vomiting and diarrhea can make detox almost impossible if you’re trying to do it on your own. Getting through these in the first few days without falling back on Percocet use is the key to a successful detox.
  • Days 4-7: Your first week of detox will have you experiencing a range of physical symptoms. Acute withdrawal symptoms include cramping, chills, and insomnia. At this stage, you may also experience cravings for Percocet, which you must learn how to cope with in order to experience long-term success. This is where counseling helps.
  • Week 2: After 7 days of detox, you should be ready to enter a drug rehab program. Although you may still experience physical pain, as well as feeling tired and needing more sleep, this is the stage in which emotional issues like depression and anxiety start to become real issues. Again, counseling and group therapy are needed to deal with these.
  • Weeks 3 & 4: Chronic users may experience prolonged withdrawal into weeks 3 and 4. Symptoms may continue to linger well beyond the first month. Be prepared for some hard work ahead. This is where it really helps to have professionals assisting you.

Percocet Detox Process

Detoxification is a natural process the body undergoes to rid itself of toxins. This process can be moderately painful for those who have developed a dependence to or who are addicted to a drug. Prescription opioid detox — including Percocet detox — is notorious for being particularly unpleasant and difficult due to the nature of the drug and how it affects the brain.

During Percocet detox, which normally lasts 5-7 days, a person will experience withdrawal symptoms. Some of the most common are vomiting, diarrhea and sweating — all ways of expelling Percocet and its chemicals from the body. This can make detoxification dangerous, however, because in the process of losing these liquids, a person can easily become dehydrated and nutrient deficient.

For this reason, it’s especially important for those undergoing detox to do so carefully in a medically-supervised environment. Detox centers or rehab facilities such as The Recovery Village offer 24/7 medical supervision for those detoxing from Percocet. Our nurses and doctors will make sure you’re fully hydrated, your electrolytes and other nutrients are maintained and your pain is at a manageable level. When medically appropriate, we use detox medication to aid patients who experience severe pain during withdrawal.

During your detox at The Recovery Village, we will also work with you to develop a plan for further drug treatment and recovery. Detoxification is merely the first step in the long process that is recovery.

Medication-Assisted Detox

Certain medications can mimic the effect of Percocet in the brain, “tricking” it into thinking you are receiving the drug when you are not and therefore lessening the severity of withdrawal symptoms. Our doctors at The Recovery Village determine on a case-by-case basis whether using certain medications to ease your withdrawal is right for you.

Some medications used to detox from Percocet and other prescription opioids include:

Strategies for Quitting Percocet at Home

There are two common strategies for quitting Percocet — all at once, also known as cold turkey, or tapered. Withdrawal can make both of these methods difficult. When quitting cold turkey, withdrawal symptoms will begin sooner and feel more severe because of the sudden lack of Percocet in your system. Tapering, or reducing the amount of drug dosage over time, can ease these withdrawal symptoms but is often difficult to maintain because it requires strong willpower. Tapering also makes withdrawal last longer, drawing out the symptoms for weeks or months, potentially.

Some also believe in the power of alternative or home therapies to manage withdrawal symptoms, although there is typically limited scientific research or evidence to support these theories. A few popular home remedies for Percocet withdrawal include getting acupuncture, drinking ginseng tea and taking u’finer or Tai-Kang-Ning supplements.

In both cases, opioid withdrawal can be dangerous and potentially life-threatening. It’s recommended that you undergo detox in a medical facility, such as a hospital or detox center, to avoid these adverse symptoms.

Visit the following websites to learn about The Recovery Village’s network of drug and alcohol rehabilitation facilities. Call today for admissions. Each center is ready to help people learn how to cope with their addiction and uncover the root causes for their substance use disorder.

  • Orlando Recovery Center: A premier rehabilitation facility in Orlando, Florida that helps individuals recover from addiction and substance use disorders. The center also offers the opportunity to treat co-occurring disorders.
  • The Recovery Village Columbus: Located in Ohio, this facility provides inpatient, outpatient and aftercare treatment for people looking to begin detox. The center provides individualized plans to help patients through recovery while addressing their unique co-occurring disorders or any setbacks that may happen during recovery.
  • The Recovery Village Palmer Lake: In Colorado, this facility offers inpatient, outpatient and intensive outpatient treatment for individuals looking to kick-start their journey to recovery.
  • The Recovery Village Ridgefield: Located right in southern Washington, this facility provides patients with outpatient and aftercare programs. Just 20 minutes outside of Portland, this facility assists individuals who are ready to begin treatment.
  • The Recovery Village: In Umatilla, Florida, this is a rehabilitation facility that provides resources for individuals seeking drug and alcohol treatment. There are inpatient, outpatient, intensive outpatient and partial hospitalization treatment programs available for those suffering from Ambien addiction.
  • IAFF Center of Excellence: Specializes in assisting firefighters who struggle with behavioral health problems and addiction. Members can enter the recovery process sooner so they can return back to work as quickly as possible. Inpatient, partial hospitalization and intensive outpatient programs are all available at this facility, where patients can address their Ambien addiction in a safe, supportive environment.
  • Denver Mental Health & Counseling: Denver Mental Health and Counseling by The Recovery Village is a physician-led outpatient center specializing in evidence-based addiction and mental health treatments, offering services such as TMS, IOP, and personalized care for both ongoing and new patients, dedicated to fostering long-term recovery and overall well-being.
  • The Recovery Village Palm Beach at Baptist Health: The Recovery Village Palm Beach at Baptist Health is a premier physician-led treatment center in South Florida, offering a comprehensive spectrum of services from medical detox to outpatient programs for alcohol, drug, and co-occurring mental health conditions, with a commitment to rejuvenating lives, families, and communities, and facilitating same-day admissions.
  • The Recovery Village Atlanta: Located in Roswell just outside downtown Atlanta, is a 62-bed physician-led treatment facility offering a comprehensive range of services, from medical detox to outpatient care, specializing in alcohol, drug, and co-occurring mental health conditions, dedicated to transforming lives, families, and communities throughout Georgia.
  • The Recovery Village Kansas City: The Recovery Village Kansas City, an 80-bed facility in Raytown just 10 miles from downtown, offers a comprehensive range of evidence-based treatments for addiction and mental health conditions, overseen by physician leaders, and is dedicated to revitalizing lives, families, and communities throughout the Midwest.
  • The Recovery Village Cherry Hill at Cooper Health: The Recovery Village Cherry Hill at Cooper, situated just 20 minutes from Philadelphia, is a leading rehab facility in South Jersey providing comprehensive, evidence-based addiction and mental health treatments, ranging from medical detox to teletherapy, with a dedicated team committed to guiding adults on their path to lifelong recovery.
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Editor – Renee Deveney
As a contributor for Advanced Recovery Systems, Renee Deveney is passionate about helping people struggling with substance use disorder. With a family history of addiction, Renee is committed to opening up a proactive dialogue about substance use and mental health. Read more
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Medically Reviewed By – Dr. Obianuju Helen Okoye, MD, MBA, MS-Epi
Dr Helen Okoye is a highly accomplished and sought after American Public Health Physician with a medical degree (MD), an MBA in Healthcare Management, and a master's in Epidemiology/Public Health. Read more

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Kosten, Thomas R, and Tony P George. “The neurobiology of opioid dependence: i[…]tions for treatment.” Science & practice perspectives vol. 1, 2002. Accessed February 10, 2021.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.