Oxaydo is a relatively new, brand-name, prescription drug. It’s a single-drug formulation of the opioid pain medication oxycodone. Oxaydo is prescribed to patients with severe, acute pain, and it’s taken on an as-needed basis. Oxaydo should only be prescribed to patients who can’t use other treatment options. Oxaydo has a misuse-deterrent feature built into the formulation to prevent intranasal misuse. If someone tries to disrupt the tablets in any way and then snort them, they should feel a burning sensation in their nose. Despite this, there is a black box warning that comes with Oxaydo regarding the high risk of misuse, addiction, and dependence associated with its use. Oxaydo shouldn’t be prescribed to people with conditions causing significant respiratory depression or people with a history of substance misuse.
The active ingredient in Oxaydo is oxycodone. Oxycodone is an opioid, also called a narcotic. Opioids are drugs that affect the central nervous system. Opioids include prescription drugs and also heroin. According to the DEA, most opioids like oxycodone are Schedule II controlled substances in the U.S. A drug classified as Schedule II is one seen as having a high potential for severe addiction and dependence. Despite the fact that it’s illegal to use oxycodone and other Schedule II drugs without a legitimate prescription, they are often diverted from medical use, which is part of the opioid epidemic in the U.S. Drugs that are Schedule II are supposed to face strict guidelines and regulations in terms of how they’re used but also prescribed and dispensed. When someone is prescribed a Schedule II drug like Oxaydo, there are limits to how much of it they can get each month, and doctors can only write prescriptions in 30-day increments. Patients also have to regularly visit their doctor to get a new prescription.
Oxycodone is undoubtedly one of the most problematic opioids in the U.S. right now. Despite its associations with addiction and overdose deaths, it continues to be widely prescribed, making it very available. Oxycodone is a powerful opioid, and when it’s misused, it can cause a euphoric high. OxyContin is one of the most commonly misused drugs containing oxycodone. Oxycodone is also found in Percodan, which is a combination of oxycodone and aspirin. Percocet is another commonly misused drug containing oxycodone as well as acetaminophen.
Oxaydo’s active ingredient oxycodone activates opioid receptors found throughout the body. Primarily, opioid drugs like Oxaydo affect the receptor sites in the brain and central nervous system as well as the gastrointestinal tract. When opioid sites are activated, it changes the transmission of pain signals between the body and brain, reducing the amount of pain a person feels. Some people will feel euphoria or pleasant feelings when they use a drug like Oxaydo because it can affect feel-good brain chemicals like dopamine. Those effects on the brain and namely neurotransmitters like dopamine can lead to addiction. Oxaydo also slows down the central nervous system. Side effects of Oxaydo can include drowsiness, dizziness and sedation. Oxaydo slows the movement of the gastrointestinal system, which can cause nausea, vomiting and constipation.
The half-life of oxycodone, the active ingredient in Oxaydo, is just over three hours on average. The average half-life range of oxycodone is around 3.2 to 5.5 hours. It can take approximately five half-lives for a drug to leave the system of an individual fully. Based on those calculations, it could take around 20 hours for a dose of Oxaydo to be eliminated from the system of an individual.
While the above estimates of how long Oxaydo stays in your system are true for the average person, everyone is going to vary a bit in how long it takes a drug to leave their system. There are factors that play a role in how long Oxaydo stays in your system as well as situational considerations. Some of the factors that influence how long Oxaydo stays in your system include:
- People with faster metabolisms will usually eliminate substances from their system more quickly than people with slower metabolisms if all other factors are the same.
- Older people will take longer to excrete a drug like Oxaydo than younger people in many cases.
- If you’re well-hydrated, you will tend to excrete Oxaydo from your system more quickly than someone who isn’t properly hydrated. The pH of a person’s urine can also play a role in how long Oxaydo stays in their system.
- If someone takes a drug like Oxaydo often, it may accumulate in their system and take longer for it to be eliminated.
- Kidney and liver function play a significant role in how long Oxaydo stays in your system.
- If you use other substances such as alcohol, other prescription medications or illicit drugs, it can take longer for Oxaydo to leave your system.
Oxycodone, the active ingredient in Oxaydo, can be detected in most standard drug tests. This can include drug testing done for employment, medical and forensic purposes. When someone uses Oxaydo, it can be detectable in a urine test for anywhere from three to four days in the average person. In a hair test, oxycodone can be detected for up to 90 days after it was last used. In a blood test, there is the shortest detection window for drug use. The use of Oxaydo might show up in a blood test for up to 24 hours after it’s used.
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