Onsolis Withdrawal and Detox

Onsolis Addiction Hotline

24/7, Toll-Free, Confidential


Onsolis is a prescription medication given to patients to manage breakthrough pain. Onsolis is primarily used by adult patients who have developed a tolerance to opioid therapy for persistent cancer pain. The medication is classified as an opioid analgesic. It reduces cancer patients’ pain by changing the way the brain responds to pain signals.

Beginning Onsolis treatment may produce side effects for some patients. Less serious side effects of Onsolis include nausea, constipation, vomiting, dizziness, drowsiness, headache, feeling weak or tired, swelling of the hands or feet, and pain or mouth sores where the medicine was placed. If these less serious Onsolis side effects do not go away over time or get worse, be sure to let your doctor or pharmacist know as soon as possible.

You should stop taking Onsolis if you experience serious side effects of Onsolis such as weak or shallow breathing, pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating, feeling very thirsty, feeling hot, being unable to urinate, heavy sweating, hot skin, and dry skin. Seek emergency medical help as soon as possible if you notice signs of an allergic reaction to Onsolis -hives, difficulty breathing, swelling of the face, and swelling of the tongue or throat.

Onsolis Withdrawal and Detox

Patients who no longer want to treat their cancer-related pain with Onsolis should first set up a meeting with their doctor before adjusting their treatment schedule. Onsolis should not be stopped suddenly or “cold turkey,” as this can produce severe Onsolis withdrawal symptoms. Most doctors will gradually lower a patient’s dosage over time so that their body can adjust appropriately to less and less of the medication. This tapering off effect will help Onsolis patients avoid extreme withdrawal symptoms from the medication.

Remember, you should never adjust your Onsolis dosage levels or treatment schedule without first consulting your doctor.

Although withdrawal symptoms can vary from patient to patient, common withdrawal symptoms include restlessness, watery eyes, runny nose, yawning, sweating, chills, muscle pain, dilated pupils, irritability, anxiety, backaches, joint pain, weakness, abdominal cramps, insomnia, nausea, loss of appetite, vomiting, diarrhea, high blood pressure, fast breathing, and increased heart rate.
Onsolis Withdrawal and Detox
All patients experience the withdrawal timeline differently since each patient has a unique physiology that determines how quickly the body processes medications. Other factors, such as how long you have been using Onsolis and your Onsolis dosage levels, will affect how quickly Onsolis withdrawal symptoms subside. In most cases, patients will recover from Onsolis withdrawal symptoms in 5 to 7 days. Some patients may take a longer or shorter time, however.
If for any reason you are having difficulty managing withdrawal Onsolis symptoms, you may want to seek a medically-assisted detoxification program. In this type of program, patients can access medical professionals while Onsolis is removed from the body. You should never be afraid to ask for help during this difficult time, as all patients experience Onsolis withdrawal differently.
It is very important for Onsolis patients to keep an updated list of their current medications handy and to share this with their doctor. Onsolis can dangerously interact with other drugs, herbal products and over-the-counter medications.

Specifically, the following substances should be avoided while using Onsolis: indinavir, nelfinavir, ritonavir, clarithromycin, itraconazole, ketoconazole, nefazodone, saquinavir, telithromycin, aprepitant, diltiazem, erythromycin, fluconazole, grapefruit juice, verapamil, and cimetidine. These should be avoided as they can dangerously increase fentanyl plasma concentrations -which can increase a patient’s risk for side effects and potentially cause fatal respiratory depression.

Other medications can also decrease the effectiveness of Onsolis, including barbiturates, carbamazepine, efavirenz, glucocorticoids, modafinil, nevirapine, oxcarbazepine, phenobarbital, phenytoin, pioglitazone, rifabutin, rifampin, St. John’s wort, and troglitazone.

Finding an Onsolis detox center to fit your recovery needs is an important step in living a happier, healthier, substance-free life. You may want to ask your doctor about what features you should look for in an Onsolis center when making this important decision.

If you or someone you love is struggling with a substance use disorder, get help right away. The Recovery Village has many treatment options and resources for those who want to recover. For more information, go online to www.TheRecoveryVillage.com or call our toll-free hotline, which is open 24 hours a day, at 855-548-9825

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.