How Long Does Onfi (Clobazam) Stay in Your System?
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Even though Onfi has a relatively fast onset of action, it is considered to be a long-acting benzodiazepine. It can take anywhere from a half-hour to two hours for the concentration of Onfi to peak in the blood when an oral suspension is used. With the tablet form of Onfi, peak concentration levels can occur anywhere from a half-hour to four hours later. The effects of Onfi can last anywhere from five to nine days.
The half-life elimination time for children who take Onfi is around 16 hours. For adults, it’s between 36 and 42 hours. There is also a metabolite left behind by Onfi that has a half-life of up to 82 hours. Due to the extended action of the drug, Onfi can show up on drug screens for an extended period of time. Any drug with such a long-lasting presence also accumulates in the body. If someone has taken Onfi several times in a relatively short period, they could have a significant accumulation of the drug in their body. This could increase their risk of an overdose.
Certain individual factors can play a role in how long something like Onfi stays in the system as well. For example, people with hepatic impairments should take lower doses, based on their doctor’s recommendations. This is because Onfi is mostly metabolized in the liver. The age of the individual is another factor that affects how long Onfi stays in the system. Often, elderly patients are advised to take lower doses of any benzodiazepine, including Onfi.
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