As is the case with any anti-depressant, Ludiomil (known by its generic name as maprotiline) is not classified as physically addictive. However, a psychological addiction may occur with extended use or misuse of the drug. This may result in certain withdrawal symptoms, which are frequently seen when treatment with maprotiline is stopped abruptly. These symptoms include, but are not limited to, agitation, anxiety, insomnia and sometimes activation of mania or rebound depression. These signs are not necessarily indicative of addiction; however, those with a history of antidepressant misuse may be more likely to experience withdrawal symptoms.
The duration and intensity of these symptoms vary, meaning it can change from person to person. It depends on a variety of factors, including age, genetic makeup, dosage and length of time taking maprotiline. For example, those taking a higher dosage over a longer period may experience a more intense bout of withdrawal symptoms (anxiety, aggression, insomnia) than someone who took the lowest dosage for the same amount of time. They will also have a higher concentration of Ludiomil in their system, and for that reason, they will likely experience a longer duration of these side effects. Elderly patients are also particularly sensitive to neurological, psychiatric or cardiovascular effects when stopping taking maprotiline, so it is important to consider age as a factor as well.
That being said, maprotiline is eliminated from the blood with a mean half-life of approximately 43 to 45 hours. This means that someone taking a dosage of 50 mg will have 25 mg left in their system after 43 to 45 hours, and 12.5 mg after another 43 to 45 hours, and so on, until it is eliminated from the body.
For those wishing to stop taking Ludiomil, it is recommended to reduce the daily dose gradually by approximately 25 percent each week. This is done to reduce the possibility of withdrawal symptoms and side effects.
If you and your doctor decide it is time for you to stop taking maprotiline, it is possible to avoid discontinuation syndrome and its adverse effects. What is important to remember is not to quit taking Ludiomil cold turkey and instead taper off the medication. This can be done by talking with your doctor and coming up with a usage plan to gradually decrease your dose over an extended period. As mentioned above, each person’s plan will vary according to a variety of factors, including age (older people are more likely to experience adverse effects), how long you’ve been taking the drug (more maprotiline in your system) and how high your dosage is (those on a low dose will be able to taper off more quickly). These are just a few of the factors that you and your doctor will consider, so be sure to remain open and transparent to reduce the risk of withdrawal symptoms.
Though, sometimes, even those who are slow and deliberate while weaning themselves off Ludiomil will experience withdrawal symptoms. One way to get relief is using another medication, namely a 20-mg dose of Prozac, another type of antidepressant with a longer half-life. This means that you won’t have withdrawal symptoms after taking that one capsule. Any adverse symptoms will likely go away within a few hours of taking Prozac.
If treatment must be stopped at once due to medical reasons, the use of a benzodiazepine for a maximum of four weeks as needed will likely suppress symptoms of withdrawal and discontinuation syndrome.
There are quite a few rehab centers that specialize in treating patients with dependencies and addictions to antidepressants. Talk with a licensed therapist or doctor while deciding upon the proper plan, and take into careful consideration the pros and cons of inpatient facilities versus outpatient clinics.
Inpatient facilities provide rooms, food and treatment for patients, which gives someone struggling with maprotiline withdrawal time to focus completely on rehabilitation. Often, they are living with patients struggling with the same thing, so the bonding and support in this program are unmatched.
For those suffering from mild-to-moderate addictions, they typically go towards outpatient services. This allows a patient to live at home, attend school or work, and still participate in their usual activities. It is less intense than inpatient facilities; though, it may take longer for someone struggling with Ludiomil withdrawal symptoms to fully recover. These facilities or clinics may offer hourly therapies, doctors’ appointments and other programs that patients can attend when they have the time.
As always, it is important to remember that you are not alone. If you or a loved one is struggling with substance use disorder, don’t delay. Contact us online or call 24/7 to our confidential helpline at 877-624-2936 to learn more about the road to recovery. We want to help.
The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.