Emsam Withdrawal and Detox
- 1. Emsam (Selegiline) Withdrawal and Detox
- 2. What Are Common Emsam (Selegiline) Withdrawal Symptoms?
- 3. Emsam (Selegiline) Withdrawal Timeline and Symptom Durations
- 4. Managing Withdrawal Symptoms of Emsam (Selegiline)
- 5. Emsam (Selegiline) Medications and Detox
- 6. How to Choose an Emsam (Selegiline) Center
Emsam increases the expression the neurotransmitters dopamine and norepinephrine. Selegiline is different from older generation MAO inhibitors in that it targets MAO-B pathways while neglecting MAO-A pathways. This results in fewer complications and milder side effects. However, like first-generation MAO inhibitors, Emsam’s effects are irreversible. This means that even after the patient stops taking Emsam, the brain will continue to inhibit the breakdown of certain neurotransmitters in the brain. In high doses, selegiline loses its MAO-B specificity and begins to target both MAO-A and MAO-B pathways.
Emsam is taken orally when used as a treatment for Parkinson’s disease. Selegiline is often used in conjunction with L-DOPA, a protein that functions as a precursor to the neurotransmitter dopamine. Treating Parkinson’s patients with both L-DOPA and Emsam allows doctors to reduce the necessary dose of L-DOPA.
Researchers have created a transdermal patch form of the drug for treatment of depression. The majority of the side effects of selegiline are due to dopamine levels becoming too high. Side effects of the pill form of Emsam may include confusion, depression, nausea, insomnia, hallucinations, poor balance, involuntary muscle movements, slow or irregular heart rate, delusions, chest pain, and syncope (fainting). Common side effects of the patch include insomnia, sore throat, diarrhea, and agitation of the skin at the patch site.
Emsam, like all MAO inhibitors, should not be mixed with foods or alcohol that contain the nutrient tyramine. When selegiline combines with high levels of tyramine, it can lead to a hypertensive crisis. Individuals on a low dose of the patch are able to continue consuming tyramine-containing foods. Patients taking higher doses are advised to eat a low-tyramine diet.
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