How Long Does Centrax Stay in Your System?
Benzodiazepines all have very similar mechanisms of action. Where they differ, however, is in how quickly they take effect and how long the effects last. Some benzodiazepines have a short onset of action, meaning that once someone takes the drug, it starts affecting them quickly. This rapid onset of action makes certain benzos more addictive than others. The quicker a drug starts working, the more addictive it may be. There are also benzodiazepines that are short-acting or long-acting. This refers to how long they remain in the system and work. Some benzodiazepines last only a few hours, while others can provide effects for days. Longer-acting benzodiazepines tend to accumulate in the system.

Centrax is one of the longest-lasting benzodiazepines available, with an active metabolite half-life of 29 to 224 hours. This means that it could take more than 400 hours to fully eliminate one specific metabolite left behind by the drug. Many drug tests are designed to screen for metabolites of parent drugs, which often remain much longer.
Since Centrax leaves behind a metabolite that can stay in the body for so long, this drug may show up on a drug test for much longer than most other substances. Centrax also starts working very quickly. Its onset of action is about 30 minutes and the duration of the effects last around 12 hours. It is likely that Centrax will accumulate in the system, so it is especially dangerous to mix the drug with opioids, alcohol or other central nervous system depressants.
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Read the most frequently asked questionsSeeking addiction treatment can feel overwhelming. We know the struggle, which is why we're uniquely qualified to help.
Your call is confidential, and there's no pressure to commit to treatment until you're ready. As a voluntary facility, we're here to help you heal -- on your terms. Our sole focus is getting you back to the healthy, sober life you deserve, and we are ready and waiting to answer your questions or concerns 24/7.
Speak with an Intake Coordination Specialist now.352.771.2700