How Long Does Buprenex Stay in Your System?

Buprenex is a partial opioid agonist, which is administered in a hospital setting by injection into the muscle or intravenously. Pain relief will begin in as little as 15 minutes after the injection and the effects will last approximately 6 hours. Buprenex will stay in your system between 7 and 40 hours from your last dose. The exact amount of time Buprenex will stay in your system will vary depending on several factors detailed below.

Inform your doctor if you are experiencing any side effects from Buprenex and avoid any interactive medications while it remains in your system -especially alcohol and any other central nervous system depressant drugs.

If you’re unsure about the safety of taking other medications and drinking alcohol while receiving the prescription or after you’ve been treated with Buprenex, talk to your doctor.

Buprenex Prescription Facts

Buprenex is a partial opioid agonist and is a powerful narcotic. This prescription contains buprenorphine and is designed to be injected into the muscle or given intravenously. It’s often used for patients who are suffering from moderate to severe acute pain.

Common side effects from Buprenex are nausea, dizziness, sweating, hypotension, vomiting, headache, and hypoventilation.

Other side effects from Buprenex may also occur, but are less common. These side effects can include:

  • Slow or racing heart rate
  • Weak or shallow breathing
  • Blurred or double vision
  • Constipation
  • Confusion
  • Severe dizziness
  • Weakness
  • Itchiness
  • Tenderness at the injection site
  • Depression
  • Nervousness
  • Tremors
  • Coma

If you experience any side effects or notice any changes after receiving a dose of Buprenex, inform your doctor right away as some of these may be serious. You can decide together if Buprenex is the right medication for your pain.

Buprenex Regulations

Buprenex is a Schedule II controlled substance in the United States.

Although there is a lower chance of addiction to Buprenex compared to other opioids, it’s still possible. Do not abruptly stop taking Buprenex, if you’ve been taking the medication for a long time because there may be withdrawal symptoms.

Most Commonly Abused Drugs Containing Buprenex

Buprenex is not contained in any other drugs, but it does contain buprenorphine as its active ingredient. Buprenorphine is sometimes used in place of heroin because it has similar euphoric effects. Although it’s not contained in other medication, those who have been using Buprenex (or buprenorphine) will find it difficult to get relief from any other opioid.

How Buprenex Affects the Brain and Body

Buprenex affects your central nervous system by changing the way your body feels pain. In doing so, it also depresses your respiratory system and has a chance of causing hypotension. This prescription medication also affects the gastrointestinal and immune systems.

Do not abruptly stop taking Buprenex or any opioid, as there may be withdrawal symptoms. Consult your doctor instead.

Half-Life of Buprenex

The half-life of a medication is the time it takes for the effectiveness to be cut in half after a person stops taking the last dose. The half-life for Buprenex is 1.2 to 7.2 hours, with an average of 2.2 hours.

Factors That Influence How Long Buprenex Stays in Your System

There are several factors that influence how long Buprenex will stay in your system after your last dose. These factors include age, gender, liver and kidney function, dosage, and length of time taking the prescription.

Your doctor can help you figure out the approximate time frame that Buprenex will stay in your system. Inform your doctor of your complete medical history, so that they can accurately help you.

Related Topic: How long does suboxone stay in your system

How Long Does Buprenex Stay in Your Urine, Hair and Blood?

Buprenex will show up in a drug test screening, so it’s important to inform your drug test administrator that you are have recently taken this prescription drug. Buprenex will stay in your urine and blood for at least 3 days, but will stay in your hair considerably longer. Drug tests on your hair can show traces of Buprenex and other prescription and non-prescription drugs for up to 90 days after your last dose.

If you feel that you or a loved one is misusing or abusing Buprenex, don’t wait to get help. Go online to or call 24/7 to our toll-free hotline at 855-548-9825 to learn more about the road to recovery. We can help you begin to overcome your addiction today.

Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.