How Long Does Atomoxetine Stay In Your System?

Atomoxetine is a medication given to people who have been diagnosed with attention-deficit hyperactivity disorder, also known as ADHD. When ADHD patients begin using atomoxetine, they may see improvement in their attention span, focus, concentration and ability to stop fidgeting.

Beginning treatment with a new medication can produce certain side effects, and atomoxetine is no different. Common side effects of using atomoxetine are an upset stomach, nausea, vomiting, constipation, tiredness, loss of appetite, weight loss, dry mouth, dizziness, drowsiness, a rise in blood pressure, trouble sleeping and decreased sexual ability or desire. Some female ADHD patients have also experienced menstrual cramps or irregular periods after they started using atomoxetine. Tell your doctor if any of these common side effects of atomoxetine persist or worsen over time.

Though uncommon, some patients do experience more severe atomoxetine side effects. Serious side effects of atomoxetine include difficulty urinating, unusual or irregular heartbeat, fainting, numbness and tingling. Using atomoxetine has also lead to liver disease in some rare cases. Get medical attention as soon as possible if you experience liver damage symptoms such as dark urine, persistent nausea, persistent vomiting, loss of appetite, stomach or abdominal pain, and yellowing skin or eyes after using atomoxetine.

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Atomoxetine has a relatively short half-life, which means it does not stay in patients’ bodies for a very long time. However, because each patient has a unique physiology, atomoxetine may take longer to get out of one patient’s system than another’s.

Nearly ten percent of all the children between the ages of two and 17 in the United States have been diagnosed with ADHD. Here are some more statistics on children with ADHD in the United States:

  • Nearly two out of every three kids with ADHD have at least one other mental, emotional or behavioral disorder.
  • One-third of children with ADHD have anxiety.
  • Nearly half of children with ADHD have a behavior problem.
  • Other conditions commonly found in patients with ADHD include depression, autism spectrum disorder and Tourette Syndrome.
Atomoxetine How Long Does It Stay In Your System?
Never take atomoxetine if you have not been prescribed it by your doctor. Do not misuse or take atomoxetine recreationally, as this can produce severe and unwanted side effects. If you notice atomoxetine misuse in yourself or someone you love, get the help you need as soon as possible.
The most commonly misused drugs that contain atomoxetine is atomoxetine itself and its name-brand version, Strattera. Do not take atomoxetine unless it has been prescribed to you.
Atomoxetine is an effective ADHD medication because it balances one of the brain’s naturally occurring neurotransmitter, norepinephrine. Norepinephrine acts as a stimulant in the central nervous system. When people have high levels of norepinephrine in the brain, they are more alert and ready for action.
After taking atomoxetine orally, the medication reaches a maximum plasma concentration within one to two hours. Atomoxetine has a relatively short half-life of about 5.2 hours in patients with a fast metabolism. Other patients who have a slower metabolism may experience an atomoxetine half-life of 21.6 hours.

Several factors influence how long atomoxetine stays in each patient’s system. These factors include your age, metabolism, organ function, genetics and more. It is important to never compare your atomoxetine withdrawal timeline to another patient’s, as this differs for everyone.

Atomoxetine can show up in different drug tests at varying times after you have taken the medication. Here are some estimates as to how long atomoxetine can be detected based on what type of drug test you are taking:

  • Urine: Depending on your individual metabolism, atomoxetine can be detected in your urine after a few days of its use.
  • Hair: Hair follicles tend to keep more remnants of medications in them for longer periods of time. For this reason, atomoxetine may be detected in the hair follicle up to 90 days after its use.
  • Blood: Typically, atomoxetine will not be detectable in your blood after three days of using it.

If you or someone you know is suffering from substance use disorder, get help as soon as possible. You can go online and visit or call our 24-hour, toll-free hotline at 855-548-9825 for more information.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.