Scientists continue to search for an answer to a key question: does an “addictive personality” exists?
In other words, if someone tends to become easily addicted to one substance, can they easily become addicted to another? For example, heroin and sugar cravings have recently been grouped together in media reports stating that sugar may be as addictive as heroin.
Substances like heroin are called opioids because they act on the brain’s mu-opioid receptors. Scientists have uncovered that activation and inactivation of these receptors do indeed seem to dictate eating behaviors in addition to opiate addiction, connecting opioid abuse to other markers such as dental health, diabetes risk and obesity. Drug stimulation of these mu-opioid receptors has also been linked to increased sugar cravings.
Research shows that people who have had prolonged exposure to opioid drugs demonstrate a stronger preference for sugary foods over those who have not used opiates. It was also discovered that blocking these same receptors, as done with anti-abuse drugs like naloxone and naltrexone, has either a weight-neutral or weight-loss effect. Therefore, it seems that the same areas of the brain responsible for heroin addiction are associated with sugar cravings.
Heroin use has also been linked to insulin resistance and, as a result, heroin users are at greater risk of type 2 diabetes mellitus. Both people addicted to heroin and methadone patients were found to have higher blood sugar levels and increased fasting insulin.
If you or a loved one is in recovery for heroin addiction, you may want to watch for other health risks such as diabetes. People on methadone often gain significant amounts of weight, potentially related to insulin resistance, sweets cravings and tolerance as they began to eat more food.
If you or a loved one is struggling with substance use, we’re here to help. Call The Recovery Village to speak with one of our experts to help guide you in the process of recovery.
Selleck, RA; Baldo, BA. “Feeding-modulatory effects of mu-opioids in the medial prefrontal cortex: a review of recent findings and comparison to opioid actions in the nucleus accumbens.” Psychopharmacology, 2017. Accessed July 25, 2019.
Mysels, DJ; Sullivan, MA. “The relationship between opioid and sugar intake: review of evidence and clinical applications.” J Opioid Manag, 2010. Accessed July 25, 2019.
Billes, SK; Sinnayah, P; Cowley, MA. Naltrexone/bupropion for obesity: an investigational combination pharmacotherapy for weight loss. Pharmacol Res, 2014 Jun. Accessed July 25, 2019.
Reed, JL; Ghodse, AH. “Oral glucose tolerance and hormonal response in heroin-dependent males.” British Medical Journal, 1973. Accessed July 25, 2019.
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