Palladone Withdrawal and Detox

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Palladone is a medication that is given to patients to relieve pain. It is typically given to patients who have severe pain that requires daily, around-the-clock treatment.

You may notice side effects after you begin taking Palladone. Common Palladone side effects include constipation, nausea, vomiting, nervousness, dizziness, drowsiness, itching, dry mouth, sweating, weakness, headaches, infection, low blood pressure, lightheadedness, loss of appetite, agitation, confusion, hallucinations, and temporary redness of the face. All of these common side effects of Palladone should recede over time. If they do not go away, call your doctor.

Seek medical attention immediately if you begin to experience the following symptoms after taking Palladone: seizure, fainting, and difficulty waking up.

If you are no longer interested in using Palladone to treat your pain, set up a meeting with your doctor to discuss the best way to discontinue your Palladone treatment. You should never stop taking Palladone suddenly or “cold turkey,” as this can result in severe withdrawal symptoms. In most cases, doctors will lower a patient’s Palladone dosage levels gradually so that the patient’s body can adequately handle less and less of the medication. You should never adjust your Palladone dosage levels or treatment schedule without explicit orders from your doctor.

Palladone Withdrawal and Detox

Common Palladone withdrawal symptoms include shaking, cold sweats, diarrhea, vomiting, muscle pain, body cramps, and insomnia. These withdrawal symptoms may persist for longer than normal if you abruptly stop taking Palladone.

Typically, Palladone withdrawal symptoms will peak between 14 and 21 hours after the last Palladone dose was taken. Most withdrawal symptoms should subside within 36 to 72 hours; however, these are just rough estimates of the timeline and symptom durations of Palladone withdrawal. Each patient has a unique physiology, and some may experience Palladone withdrawal for a longer period of time because it takes their body longer to rid itself of the medication. Factors that may affect your Palladone withdrawal timeline and symptom duration include age, metabolism rate, organ functions, genetics, dosage, and how long you have been taking Palladone.

If you are having trouble managing your withdrawal symptoms, you may want to look for a medically assisted detoxification program to support you during this difficult time. In a detox program, medical professionals will be present to answer any questions you may have regarding your struggle with Palladone withdrawal, as well as teach you how to cope with these symptoms. Remember, everyone experiences Palladone withdrawal differently. It is important to seek help if you need it.

Make sure that you keep a list of all your current medications, including any herbal products or over-the-counter drugs, and share this list with your doctor. This is important, as taking other substances may interact with Palladone or decrease the medication’s effectiveness.

Palladone may cause an interaction with alcohol, sedatives, hypnotics, tranquilizers, general anesthetics, phenothiazines, other opioid medications, pentazocine, nalbuphine, butorphanol, buprenorphine, MAO inhibitors, and anticholinergics.

Palladone should not be used if you are pregnant. Taking this medication while pregnant may harm the fetus and cause opioid withdrawal symptoms in your newborn baby. This medication should also be avoided if you are breastfeeding, as Palladone can pass into breast milk and harm the baby.

Only take the amount of Palladone that your doctor has prescribed. Taking large doses of Palladone may put patients at greater risk of developing a dependence or addiction.

Choosing a Palladone center is an important step in your journey to recovery. To make the most informed decision possible, it is recommended that you set up a meeting with your doctor to discuss what you may need in a Palladone treatment facility. You may want to bring up factors such as how long you have been using Palladone and your Palladone dosage levels during this important discussion.

If you or someone you know is struggling with Palladone addiction, or another form of substance use disorder, seek professional help as soon as possible. The Recovery Village offers a wide variety of programs and resources for those people who are ready to overcome their addiction for good. To learn more about these life-saving treatment options, you can go online and visit or call our toll-free hotline, which is open 24 hours a day at 855-548-9825.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.