How Long Does Paxipam (Halazepam) Stay in Your System?

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Paxipam is a prescription benzodiazepine that is used for treating anxiety. Paxipam, also known as halazepam, is no longer marketed in the United States; however, many other benzodiazepine drugs are. Benzodiazepines are a broad class of drugs that include commonly prescribed medications, such as Xanax and Klonopin. Benzodiazepines increase the effects of the calming neurotransmitter GABA, treating anxiety, insomnia, panic disorders, seizure disorders and symptoms of alcohol withdrawal.

All benzodiazepines, including Paxipam, are central nervous system depressants. They all affect the body in similar ways and can be habit-forming, causing substance use disorder. For those reasons, benzodiazepines are intended as short-term treatment medications -usually only for a few weeks. Shorter durations of usage can lower the risk of substance use disorder.

Paxipam (halazepam) How Long Does It Stay In Your System?
While most benzodiazepines provide similar effects on the brain and central nervous system, they are some slight differences between the drugs. One of the primary distinctions is in how quickly they start working in the body and how long they remain in the system. Benzodiazepines are often broken into categories: ultra-short and short-acting, intermediate-acting and long-acting. Diazepam is a fast-acting benzodiazepine drug. It usually starts working within about 30 to 60 minutes. Alprazolam, which is the generic name of Xanax, has an intermediate onset of action and lasts anywhere from 11 to 20 hours. Longer-acting benzodiazepines include flurazepam, which is sold under the brand name Dalmane.

Different benzodiazepine drugs are selected to treat different health conditions. For example, shorter-acting benzodiazepines like Xanax and Valium tend to be more effective at treating anxiety disorders. Longer-acting benzodiazepine drugs are better for treating insomnia and sleep disorders because they help people fall asleep, and more importantly, stay asleep. The shorter-acting benzodiazepines tend to carry a higher risk of substance use disorder. However, longer-acting benzodiazepines may accumulate in the system and pose a higher risk of overdose. How long a benzodiazepine stays in the system can affect drug tests as well. For example, certain benzodiazepines can show up in a urine test for up to six weeks after the last dose is taken.

Paxipam is considered to have an intermediate to slow onset of action. This means it takes Paxipam a relatively long time to start working. Paxipam reaches peak levels of concentration in the blood anywhere from 1 to 3 hours after it’s taken. It also leaves behind a metabolite which takes about 3 to 6 hours to reach its peak concentration level. The half-life of a drug is a measure of how long it takes the body to remove half the dose of a drug. The half-life of Paxipam is about 14 hours. The metabolite the drug leaves behind has a long half-life of 30 to 100 hours. This means that Paxipam takes a long time to start working as compared to other benzodiazepines, as well as a very long half-life. Therefore, Paxipam can accumulate in the system and it can show up on drug tests for weeks after the last use.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.