Talwin Withdrawal and Detox

Talwin Addiction Hotline

24/7, Toll-Free, Confidential

Talwin is a potent combination medication that’s prescribed to treat moderate to severe pain. Talwin is a combination of the synthetic opioid pentazocine and the opioid antagonist naloxone.

Prior to the 1970s, pentazocine was manufactured without naloxone. Naloxone was added following a significant increase in opioid overdose cases in which recreational drug users crushed and injected the drug. Talwin is only intended to be taken orally. When taken as prescribed, the naloxone remains inactive. When users attempt to inject the drug, naloxone rapidly reverses pentazocine’s effects.

As is the case with all synthetic opioid products, Talwin can be addictive. However, Talwin has a much lower addictive potential compared to that of other opioids. This is in part due to the fact pentazocine produces a ceiling effect. At high doses, Talwin begins to lose its effectiveness. This makes the drug less appealing for people attempting to take Talwin recreationally.

Talwin’s ceiling effect also makes it significantly more difficult to result in a fatal overdose. Pentazocine is a mixed opioid agonist/antagonist. This means that it activates some opioid receptors while blocking the activity of others. Not only does this reduce the likelihood of clinically significant respiratory depression, but it also inhibits the “high” that individuals experience when taking other full opioid agonists, like morphine.

Talwin Withdrawal and Detox
Withdrawals from regular Talwin treatments are characterized by intense drug cravings and flu-like symptoms. Common symptoms of post-acute withdrawals from Talwin include hot/cold flashes, cravings, sneezing, decreased or increased sex drive, fatigue, brain fog, confusion, increased tear production, restless legs, sweating, skin-crawling, abdominal cramping, and goosebumps.

Additoinal symptoms may include high blood pressure, agitation, anxiety, cough, dehydration, muscle aches, lack of motivation, insomnia, runny nose, excessive yawning, sneezing, dilated pupils, nausea, and vomiting.

For short-acting opioids like pentazocine, post-acute withdrawals typically begin within 6 to 12 hours following the time of the last dose.

The first three days of withdrawals are characterized by high blood pressure, hot/cold flashes, cravings, sneezing, dehydration, muscle aches, lack of motivation, insomnia, runny nose, and excessive yawning. Other early symptoms may include agitation, anxiety, cough, fatigue, confusion, mental fog, excessive tear production, restless legs, skin-crawling, and excessive sweating.

The later withdrawal symptoms usually begin at day three and last at least a week. These can include abdominal cramping, diarrhea, goosebumps, sneezing, dilated pupils, depression, nausea, and vomiting. Withdrawal symptoms can last up to several weeks for some patients.

The psychological urge to take certain drugs continues indefinitely for many individuals. A percentage of patients recovering from opioid misuse take therapeutic doses of long-acting opioids for many years before discontinuing use. Others remain on doctor-prescribed doses of medications like methadone for the rest of their lives. These patients do not experience a “high” from methadone treatment, rather, it mitigates the severity of drug cravings and the urge to misuse the drug.

Incorporating healthy lifestyle habits can help patients manage Talwin withdrawals. Mild to moderate exercise can help activate the brain’s healing processes and balance hormone levels. Adrenal insufficiency is a common adverse effect of long-term opioid consumption. Symptoms of adrenal insufficiency include chronic fatigue and brain fog. Adrenal insufficiency occurs when the adrenal gland can’t keep up with the body’s demands for the stress hormone cortisol.

Eating healthy foods can help restore damage that has occurred to organs in the body. The liver is primarily responsible for metabolizing Talwin. Eating plenty of dense, leafy greens can help cleanse the liver and return it to optimal functionality.

Several medications and treatments can help ease the severity of Talwin withdrawals. In a medical setting, intravenous fluids can be administered to ensure adequate hydration. Medications can be given to address specific symptoms of Talwin withdrawals, including nausea, vomiting, headaches, fever, and diarrhea. I.V. fluids can be especially helpful during bouts of nausea, vomiting, and diarrhea to compensate for the fluid loss.

Opioid replacement therapy can significantly reduce the severity of drug cravings. Talwin is often replaced with longer-acting opioids that have slower onset and milder withdrawal symptoms. Doses are gradually reduced over time until the patient is ready to switch to long-term therapeutic opioids like buprenorphine or methadone.

Following medical detox, patients will have the option of enrolling in a drug treatment program. Inpatient recovery therapy typically last four weeks. Patients participate in therapy sessions with other individuals who are recovering from substance use disorders. Inpatient therapy provides patients with an environment that’s free from the temptation to take drugs so that they can focus on recovery.

If you or someone you love is struggling with opioid misuse, The Recovery Village is available to answer any questions you may have. Visit us online at www.TheRecoveryVillage.com or call our toll-free hotline at 855-548-9825 for information about recovery programs in your area. Recovery begins with a phone call, make yours today.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.