Silenor Signs, Symptoms and Side Effects
Cases of doxepin misuse and addiction are rare. The general effects of doxepin don’t make it an appealing substance to misuse. Silenor is classified as “non-addictive” by the federal government.
Silenor can trigger a wide range of anticholinergic and central nervous system (CNS) side effects. Anticholinergic side effects may include profuse sweating, constipation, difficulty urinating and dry mouth. Doxepin can impact the central nervous system by inducing drowsiness, confusion, agitation, difficulty sleeping, fatigue, lightheadedness and dizziness. On rare occasions, treatment with doxepin can result in seizures, delirium and tinnitus (ringing in the ears). Other side effects may include low blood pressure, rapid heart rate and abnormal heart rhythms. Silenor may decrease liver function in some patients.
Doxepin reduces anxiety and depression by inhibiting the reuptake of serotonin and norepinephrine from the synaptic gap between neurons. The longer these neurotransmitters can stay in the synaptic gap, the longer they can induce beneficial effects and reduce symptoms.
Silenor also acts on acetylcholine, the primary neurotransmitter of the prefrontal cortex. The prefrontal cortex is the area of the brain responsible for critical thinking. Doxepin’s ability to minimize allergic reactions is thanks to its activity on histamine receptors in the body
Although doxepin is considered non-addictive, cessation of use can trigger withdrawal-like symptoms referred to as discontinuation syndrome. Discontinuation of Silenor may result in increased insomnia, anxiety, malaise, nausea, headache or motor disturbances. Notify your doctor as soon as you experience the onset of such symptoms.
Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.
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