Provigil Mixing It With Alcohol

Provigil should not be mixed with alcohol. The combination of Provigil and alcohol can cause unpredictable side effects, including blackouts and a significantly increased alcohol tolerance.

Provigil should not be mixed with central nervous system stimulants like amphetamines or caffeine. Combining stimulants with modafinil can cause anxiety, tremors and rapid heart rate.

Never take opioids alongside Provigil. Opioids can decrease plasma levels of Provigil and reduce its effectiveness while triggering the onset of withdrawal symptoms.

Common side effects of Provigil use can include insomnia, dizziness, stomach problems, diarrhea, anxiety and nervousness. Such side effects occur in fewer than 10 percent of individuals. Headaches occur in one-third of participants in clinical trials.

Provigil Mixing It With Alcohol

Provigil is a wakefulness-promoting medication. It is commonly prescribed as a treatment for disruptive sleep disorders like narcolepsy, obstructive sleep apnea, idiopathic hypersomnia, shift work sleep disorder and excessive daytime sleepiness.

Provigil achieves its stimulating effects by selectively acting on several different neurological pathways in the brain. Its exact mechanism of action is not unknown. One of the ways that Provigil affects the brain is by blocking the function of certain dopamine transporter cells. By inhibiting the reuptake of dopamine, Provigil can help improve focus and motivation. Researchers believe that Provigil may act on the neurotransmitters serotonin and norepinephrine as well.

Provigil stimulates histamine levels in the hypothalamus. In people who are hypersensitive to Provigil, this histamine response can trigger an allergic skin reaction. Report to your doctor immediately if you experience abnormal skin irritation while taking Provigil. Your doctor will likely recommend discontinuing use if such a reaction occurs.

Provigil should not be mixed with alcohol. Independent reports from people who use the drug indicate that alcohol combined with Provigil can cause an abnormally high alcohol tolerance and lead to blackouts. Alcohol and Provigil have opposing and contradictory effects on brain chemistry. Alcohol promotes the production of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) while decreasing the production of the excitatory neurotransmitter glutamate. Provigil increases glutamate while decreasing GABA.

Individuals being social and well-spoken up until the point that their brain and body begin to shut down. Although Provigil is a widely researched drug, more clinical studies need to be conducted to better understand its effects when combined with alcohol. Based off anecdotal evidence from people who use it, it’s advised to avoid drinking alcohol while taking Provigil due to the increased likelihood of blackouts.

Provigil Mixing It With Alcohol

The most common side effect of taking Provigil is headaches. Roughly one-third of people taking Provigil will experience frequent and often severe head pain. Hypersensitivity to Provigil occurs in some patients and is expressed as a skin rash. Researchers think that these skin reactions are allergy related. Provigil should not be mixed with alcohol or opioids. Combining Provigil and alcohol can lead to an increased risk of blackouts.

Taking opioids alongside Provigil can significantly lower plasma levels of the drug and trigger the onset of Provigil withdrawal symptoms. Withdrawal from Provigil is typically mild and can include increased agitation and bouts of anger.

If you or someone you know needs help discontinuing Provigil treatment, The Recovery Village is connected to a trusted network of substance misuse therapists and recovery programs.

Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.