Parnate FAQ

For individuals being treated for major depressive disorder (MDD) who have not seen relief when using other drugs, Parnate is another option. Parnate (tranyleypromine) is in the class of drugs called monoamine oxidase inhibitors (MAOIs) that work by increasing naturally-occurring chemical substances in the brain that help a person maintain a mental balance.

As with any drug that works by affecting the brain, there are some serious side effects to watch for with Parnate. These include rapid heart rate, tremors, nausea and vomiting, headaches, vision problems, tremors, confusion, panic attacks, insomnia, agitation, hostility, aggression, increased anxiety, and suicidal thoughts.

Parnate is not physically addictive but a reliance on this drug may happen. Some users may feel that their mental state has plateaued and increase their dosage. Doing so will make their body become further tolerant to the drug, and more will be needed to achieve the same sense of well-being. This develops into a psychological addiction as the user becomes reluctant to stop using the drug, or decrease the dose back to what was recommended, out of concern for feeling worse.

If you or somebody you know has become reliant on using Parnate, you may have questions about what can be done. To learn more, check out our frequently asked questions about Parnate or contact a representative at The Recovery Village to learn about options for recovery.