Parnate (Tranylcypromine) Addiction and Abuse
When tranylcypromine is mixed other serotonergic medications, it can result in serotonin overload, psychosis, and permanent brain damage if left untreated. Patients taking an MAOI like Parnate need to refrain from ingesting foods or beverages that contain tyramine. Tyramine is present in many foods as a byproduct of fermentation. Foods like aged cheeses, meats, and chocolate are high in tyramine, as is red wine. When tyramine is present in the blood, it can trigger the release of norepinephrine.
Typically, the body would respond by slowing the release of norepinephrine and thus avoiding a spike in blood pressure. However, tranylcypromine disables this ability by preventing the breakdown of norepinephrine. The combined effects can result in a potentially life-threatening hypertensive crisis.
However, this only applies to patients who follow the prescribed dose of tranylcypromine. There have been cases of individuals taking extra large doses of the drug to experience an amplified version of the drug’s stimulating effects. People who “chase a high” in this way are prone to experience withdrawal symptoms and drug cravings like that of an amphetamine user.
If you or a loved one is struggling with substance use disorder, don’t delay. We can help you overcome your addiction today.
Seeking addiction treatment can feel overwhelming. We know the struggle, which is why we're uniquely qualified to help.
Your call is confidential, and there's no pressure to commit to treatment until you're ready. As a voluntary facility, we're here to help you heal -- on your terms. Our sole focus is getting you back to the healthy, sober life you deserve, and we are ready and waiting to answer your questions or concerns 24/7.Speak to an Intake Coordinator now.352.771.2700