How Long Does Neurontin Stay in Your System?

Neurontin is a brand-name prescription medication, which is also known as gabapentin in its generic form. Neurontin is used along with other medicines for treating and controlling seizures related to epilepsy. Neurontin is also used to treat nerve pain related to shingles. Neurontin is classified as an antiepileptic and anticonvulsant drug. When someone is prescribed Neurontin, they’re instructed to take it in a way that allows the level of the drug in their body to stay constant. For example, when Neurontin is prescribed to treat seizures, it’s taken as often as three times a day. Some of the possible common side effects of Neurontin include dizziness, coordination problems and drowsiness. Any time someone uses Neurontin outside of how it’s prescribed by a medical professional, it can be considered to be abuse.

The FDA initially approved gabapentin in 1993 as a partial seizure medication. In 2004, Neurontin was approved to treat neuropathic pain as well. There has been an increase in the number of instances of Neurontin abuse in recent years. There are several different reasons that explain this trend. First, Neurontin is not currently classified as a controlled substance in the U.S. In 2015, there were 57 million prescriptions written for the drug, making it a widely available drug. Despite the fact that it isn’t a controlled substance, people who use it can experience effects similar to those of marijuana or benzodiazepines. The potential for abuse of Neurontin is particularly high when it’s combined with other substances, such as opioids or anxiety medications. Due to the risks of abuse that are now becoming more problematic with Neurontin, some states have moved to make it more difficult for people to obtain. Others are pushing for the drug to be classified as a controlled substance at the federal level.

Neurontin affects the brain and central nervous system. When someone uses Neurontin, it calms and stabilizes how nerve messages are sent to the brain. Medical professionals believe that Neurontin affects how electrical signals accumulate in the nerve cells. Neurontin is also believed to increase the production of the natural neurotransmitter GABA. When someone uses Neurontin, the calming effects of the drug may make them feel drowsy or fatigued. Neurontin can also cause people to feel more relaxed, which is why the drug is used off-label to treat anxiety.

Neurontin has a relatively short half-life of anywhere from 5 to 7 hours, on average. This short half-life means that someone who is dependent upon Neurontin will experience withdrawal symptoms relatively quickly after they stop using it or if they wait too long between doses. Based on an average Neurontin half-life of 5 to 7 hours, Neurontin would stay in the system anywhere from 1.15 to 1.60 days. Most of the drug would leave the body after two days.
While the average time it takes for Neurontin to be eliminated is around 1 to 2 days, there are individual factors that play a role. One of the biggest factors that influences how long Neurontin stays in the system is renal function. If someone has normal renal function, they will likely excrete the drug from their system within two days. However, if someone has reduced renal function, a single dose has been shown to have a half-life of 132 hours. There are other additional individual factors that influence how long Neurontin stays in the system as well. Age is a big factor since younger people tend to eliminate medications and other substances more quickly than older people. The higher the dosage of Neurontin someone uses, the longer it will take to eliminate it. Factors like metabolism, overall health, urine pH and hydration levels can also be relevant.
People often have questions about whether Neurontin will show up on a drug test and, if so, for how long. First, Neurontin is not the same as an opioid or a benzodiazepine. It’s not going to show up on drug tests like these substances unless it is specifically tested for. However, if it were tested for, Neurontin could show up in a blood or urine test for around two days after it was last taken. In someone with kidney functionality problems, it could show up much longer. Someone with renal failure could test positive for gabapentin for around 30 days.

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