Dangers of Loperamide High
There’s a dangerous trend emerging among opioid addicts that involves the abuse of over-the-counter anti-diarrheal medication. Anti-diarrheal medication containing loperamide hydrochloride is a widely available and inexpensive over-the-counter drug that alleviates diarrhea related to common issues like traveling, overeating and minor viruses. It works by binding to opioid receptors in the intestines to reduce the intestinal hyperactivity that leads to symptoms like diarrhea and cramping. Much larger loperamide doses, however, can lead to a somewhat euphoric high similar to that of a high obtained from opioid drugs.
This condition can lead to tissue death in the intestine, infection or even sepsis, the last of which occurs when toxins from an infection build up to dangerously toxic levels in the bloodstream.
The problem with using medications containing loperamide hydrochloride for the purpose of getting high is that it requires the person taking it to ingest those drugs in amounts hundreds of times larger than the recommended dosage, which is about eight milligrams daily. The amount of loperamide needed to get high varies from person to person, but the New York Times article indicates that “lobe abusers — as they sometimes call themselves — have reported ingesting 100 two-milligram tablets daily for weeks.”
Using loperamide in this way can lead to dangerous symptoms like depression of the central nervous system, reduced respiration, severe nausea and vomiting, cardiac issues like irregular heartbeat, and even death. If an overdose is suspected as a result of a patient trying to get a loperamide hydrochloride high, the patient can be given Naloxone, just like they would for an opioid high.
If you think you or a loved one could be struggling with substance use disorder involving loperamide or other drugs, we invite you to contact our compassionate and well-trained team at The Recovery Village. We’re here to answer your questions and ready to help in any way we can.
Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.
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