Intermezzo (Zolpidem) Addiction and Abuse

Another risk of Intermezzo and zolpidem is addiction and dependence. Intermezzo is not a benzodiazepine, but it acts similarly to this drug class. Benzodiazepines include commonly abused drugs like Xanax and Klonopin. Due to the way that Intermezzo affects the brain, it may cause people to feel euphoric or pleasantly relaxed -which can often lead to addiction. If someone abuses Intermezzo, they are more at risk of becoming addicted or dependent. Intermezzo is intended only for short-term use to reduce this risk.
Intermezzo doesn’t have as high of an addiction potential as opioids, but the risk exists nonetheless. The more someone’s brain is exposed to Intermezzo, the more likely it is that substance use disorder will occur. Intermezzo, by affecting GABA, can also trigger a dopamine response -which is often how substance use disorder starts. The best way to reduce the risk of Intermezzo addiction is to use it only as prescribed. Patients should take only the prescribed dose and shouldn’t take it for longer than instructed by their doctor. Intermezzo should not be combined with other substances. Abusing Intermezzo and combining it with other substances increases the likelihood of substance use disorder and dangerous outcomes.
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Medical Disclaimer: The Recovery Village aims to improve the quality of life for people struggling with a substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare provider.
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