Duragesic Addiction Hotline
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Patients who begin to use Duragesic may notice common side effects, including nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, headaches, and mild irritation or redness at the application site. These symptoms should all go away with time. If these common Duragesic side effects persist or worsen over time, contact your doctor as soon as possible.
More serious side effects of Duragesic include mental changes, agitation, confusion, hallucinations, severe stomach or abdominal pain, difficulty urinating, slow or irregular heartbeat, loss of appetite, unusual tiredness, and weight loss. Be sure to notify your doctor or pharmacist immediately if these symptoms occur.
Get professional medical attention if you experience fainting, seizure, slow or shallow breathing, severe drowsiness, or difficulty waking up after using Duragesic.
Duragesic has the potential to interact with other medications, herbal products and over-the-counter drugs. Products which have been shown to interact with Duragesic include pain medications like pentazocine, nalbuphine, butorphanol, and naltrexone.
The following medications have been shown the decrease the effectiveness of Duragesic: cimetidine, nefazodone, azole antifungals, diltiazem, verapamil, HIV drugs, macrolide antibiotics, rifamycins, and certain anti-seizure medications such as carbamazepine and others.
Do not use MAO inhibitors while taking Duragesic, as this can produce a serious or possibly fatal interaction. Specifically, avoid the following MAO inhibitors during your Duragesic treatment: isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, and tranylcypromine.
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