- 1. How Long Does Conzip Stay In Your System?
- 2. Conzip Prescription Facts
- 3. Conzip Regulations
- 4. Most Commonly Abused Drugs Containing Conzip
- 5. How Conzip Affects The Brain And Body
- 6. Half-Life Of Conzip
- 7. Factors That Influence How Long Conzip Stays In Your System
- 8. How Long Does Conzip Stay In Your Urine, Hair And Blood?
Common side effects of Conzip use include respiratory depression, lethargy, fatigue, drowsiness, somnolence, dizziness, nausea, vomiting, constipation, excessive sweating and itchiness. The itchiness caused by Conzip does not seem to be the result of a histamine release as is the case with morphine and other synthetic opioids. Low blood pressure upon standing may also be experienced.
Conzip comes in the 100 mg, 200 mg, and 300 mg capsules. They are designed to release a percentage of the drug immediately upon ingestion, and then gradually release the remainder of the drug over an extended period. The 100 mg capsules release 25 mg immediately, while the 200 mg and 300 mg capsules release 50 mg immediately upon ingestion.
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When used recreationally, Conzip is commonly mixed with other central nervous system depressants. The combined use of Conzip with other central nervous system depressants can greatly increase the risk of life-threatening complications. The primary risk factor of Conzip use is severe respiratory depression.
Conzip should not be mixed with other opioids, benzodiazepines, non-benzodiazepine sedative/hypnotics, tranquilizers, muscle relaxants or alcohol. Conzip may conflict with these substances and can lead to extended clearance times and elevated plasma concentrations. This increases the risk of toxicity and overdose.
Conzip should not be mixed with serotonergic drugs, such as those used to treat depression. These include selective serotonin reuptake inhibitors (SSRIs) and tricyclics. The combined use of serotonergic medications with Conzip can result in a dangerous condition of serotonin overload called serotonin syndrome. Serotonin syndrome can result in psychosis and death in severe cases.
Conzip is roughly one-tenth as powerful as equivalent doses of morphine and is equal in potency to codeine and pethidine. When ingested orally, Conzip begins to take effect in about an hour.
Conzip is primarily metabolized by the liver, and its metabolites are eliminated by the kidneys. Impaired function of these organs can greatly extend clearance rates. Patients with a history of hepatic or renal failure will likely require lower doses of the drug to avoid complications related to elevated opioid plasma concentrations.
Age can be a factor due to the overall slower metabolic rates that tend to characterize elderly populations. Smaller patients typically require lower doses of Conzip to achieve the desired pain-relieving effects.
Taking certain substances with Conzip can extend clearance rates. Carbamazepine increases Conzip metabolism, leading to faster elimination times and a reduction in pain-relieving effects. Ketoconazole, erythromycin, rifampin and St. John’s Wort may also alter tramadol exposure.
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