Barbiturate Addiction

For a long time, barbiturates, a general class of sedative-hypnotic drugs, were the first-line of treatment for patients who required sedatives or anti-anxiety medications. Barbiturates have a long history. These drugs were initially used in medicine at the start of the 1900s. They became popular in the 1960s and 1970s as the go-to treatment option for anxiety, insomnia and seizure disorders. From there, they became widely used recreationally. People took them not only to feel high or relaxed, but also to eliminate some of the adverse side effects of other drugs. Overall, the use of barbiturates has gone down a great deal since the 1970s.

Now, doctors prescribe barbiturates in a much more limited manner. In some cases, barbiturates are prescribed to control symptoms of seizure disorders. They are also used to sedate patients before procedures and are less frequently prescribed to treat anxiety, insomnia and headaches. For the most part, barbiturates have been replaced with safer medications that carry fewer risks and side effects.

Barbiturate addiction is one of the primary risks associated with this drug class. Physical and psychological dependence are possible and there is a relatively high risk of overdose. Benzodiazepines have now become a preferred treatment option, as well as other sedative sleep aids such as Ambien and Sonata. When someone regularly uses any barbiturate drug, they can quickly become tolerant to it. Tolerance can occur even with one dose of barbiturates. Tolerance can, and often does, lead to dependence. When someone is dependent upon barbiturates and suddenly tries to stop using them, they will go through withdrawal -which can be deadly.

What Are Barbiturates?

Barbiturates act as central nervous system depressants. This drug class affects GABA neurotransmitters and receptors, much like benzodiazepines and prescription sleep aids. This is why barbiturates can provide a sense of relaxation, drowsiness or sedation. They slow brain activity due to their effects on GABA. However, there are specific components of barbiturates that make them more toxic than benzodiazepines if someone overdoses. People who recreationally abuse barbiturates may feel euphoric or very relaxed. When people abuse barbiturates chronically, there is a high risk of death.

What Do Barbiturates Look Like?

There are different kinds of barbiturates. These drugs can be injected into a vein or muscle, but more often they’re taken as pills. The most commonly abused barbiturates have a designated street name based on their color. For example, generic amobarbital is blue and is called “blue haven,” “blue velvet” or “blue devils.” Pentobarbital is yellow and has street names such as “yellow jackets” or “Mexican yellows.” Phenobarbital is purple and may be referred to by street names like “purple hearts.” Secobarbital is red and is called “red birds” or “red devils.” Brand name barbiturates include Butisol, Seconal, Fioricet, Fiorinal and Esgic.

Are Barbiturates Addictive?

Barbiturates are considered to have a high potential for abuse and addiction. While the use of these drugs has gone down significantly since the 1970s, they are still abused and often used to counteract the effects of stimulant drugs like cocaine. Barbiturates are also one of the drugs most commonly used in suicide attempts. Some of the signs of barbiturate abuse can include elation, reduced inhibitions, impaired judgment, and changes in mood or emotion. People using the drug may seem to be very tired, relaxed, or sedated. Other signs of barbiturate abuse can include slurred speech and confusion. Barbiturate abuse doesn’t necessarily mean someone is addicted, but using these drugs recreationally increases the chances of becoming addicted.

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FAQs


What Are Barbiturates?

Barbiturates act as central nervous system depressants. This drug class affects GABA neurotransmitters and receptors, much like benzodiazepinesand prescription sleep aids. This is why barbiturates can provide a sense of relaxation, drowsiness or sedation. They slow brain activity due to their effects on GABA. However, there are specific components of barbiturates that make them more toxic than benzodiazepines if someone overdoses. People who recreationally abuse barbiturates may feel euphoric or very relaxed. When people abuse barbiturates chronically, there is a high risk of death.

Are Barbiturates Addictive?

Barbiturates are considered to have a high potential for abuse and addiction. While the use of these drugs has gone down significantly since the 1970s, they are still abused and often used to counteract the effects of stimulant drugs like cocaine. Barbiturates are also one of the drugs most commonly used in suicide attempts. Some of the signs of barbiturate abuse can include elation, reduced inhibitions, impaired judgment, and changes in mood or emotion. People using the drug may seem to be very tired, relaxed, or sedated. Other signs of barbiturate abuse can include slurred speech and confusion. Barbiturate abuse doesn’t necessarily mean someone is addicted, but using these drugs recreationally increases the chances of becoming addicted.

Barbiturate Abuse Signs, Symptoms & Side Effects

Whenever someone is using a prescription drug in a way other than as instructed by a medical professional, it’s classified as abuse. The first signs of barbiturate abuse can be subtle. For example, a person might take more of the drug than they’re prescribed or use it more often than they’re supposed to. Using barbiturates without a prescription is also considered to be abuse. Or, using these drugs with another substance like alcohol, indicated barbiturate abuse.

Barbiturates affect GABA receptors and neurotransmitters in the brain and are considered to be central nervous system depressants. Symptoms of barbiturate abuse reflect this mechanism of action. A person who is abusing barbiturates may seem to be very relaxed, sleepy or sedated. Other symptoms of barbiturate abuse can include loss of inhibitions, problems walking and slurred speech. Symptoms of barbiturate abuse can seem similar to those of being drunk from alcohol.

Symptoms of barbiturate abuse may also include problems with cognition and judgment, lethargy, shallow breathing, or the appearance of stumbling. The dosage a person uses can impact the symptoms of barbiturate abuse. For example, in small doses, the symptoms primarily include drowsiness and disinhibition. At higher doses, a person will appear to be intoxicated. Beyond that point, symptoms can include coma or stopped breathing.

It’s very easy to become addicted to barbiturates, even after using drugs of this class only a few times. The same holds true for dependence. When someone is dependent upon barbiturates, their brain and body have become used to the presence of the drug. Stopping the use of barbiturates suddenly can cause withdrawal symptoms to surface. Barbiturate withdrawal can be severe in some cases. Psychological side effects of barbiturate abuse can include changes in mental function, hallucinations, anxiety or depression.
What Are Common Barbiturate Withdrawal Symptoms?

When someone is dependent upon barbiturates, they may experience withdrawal symptoms when they suddenly try to stop using them. Withdrawal can include physical and psychological symptoms, although it’s different from addiction. Withdrawal is a group of symptoms that can be physically uncomfortable and, in some cases, life-threatening. Some of the common barbiturate withdrawal symptoms include:

  • Agitation
  • Anxiety
  • Insomnia
  • Raised body temperature
  • Hallucinations
  • Shakiness
  • Tremors
  • Changes in behavior
  • Aggression
  • Seizures
Medical Disclaimer

The Recovery Village aims to improve the quality of life for people struggling with substance use or mental health disorder with fact-based content about the nature of behavioral health conditions, treatment options and their related outcomes. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. The information we provide is not intended to be a substitute for professional medical advice, diagnosis or treatment. It should not be used in place of the advice of your physician or other qualified healthcare providers.